220666-10-4

Basic information

• Product Name: Propanenitrile, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2S)- (9CI)
• Synonyms: Propanenitrile, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2S)- (9CI)
• CAS NO: 220666-10-4
• Molecular Formula: C8H13NO2
• Molecular Weight: 155.19432
• Product Categories: METHOXY
• Mol File: 220666-10-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanenitrile, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Propanenitrile, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2S)- (9CI)(220666-10-4)
• EPA Substance Registry System: Propanenitrile, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, (2S)- (9CI)(220666-10-4)

Safety Data

• Hazardous Substances Data: 220666-10-4(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 87834-47-7 (-)-2-hydroxypropionitrile 

Downstream Products

• 152519-33-0 (S)-2-hydroxyhexan-⁽³⁾-one 
• 84435-13-2 (+)-(2S)-2-hydroxyoctan-3-one 

Relevant articles and documents

Asymmetric reduction of α-keto esters and α-diketones with a bakers' yeast keto ester reductase

Optically pure α-hydroxy esters and α-hydroxy ketones have been synthesized by the reduction of the corresponding ketones with a keto ester reductase isolated from bakers' yeast (YKER-I). The reduction of α-keto esters affords the corresponding (S)- or (R)-hydroxy esters selectively, where the stereochemical course depends on the chain length of the alkyl substituent on the carbonyl group. An α-keto short alkanoic ester affords the corresponding (S)-hydroxy ester, whereas a long alkanoate yields the corresponding (R)-hydroxy ester. The reduction of α-diketones affords the corresponding (S)-2-hydroxy ketones regio- and stereoselectively.