220677-29-2Relevant articles and documents
N-Benzylindole-2-carboxylic acids: Potent functional antagonists of the CCR2b chemokine receptor
Kettle, Jason G.,Faull, Alan W.,Barker, Andy J.,Davies, D. Huw,Stone, Michael A.
, p. 405 - 408 (2007/10/03)
Screening of the corporate database led to the discovery of a novel series of N-benzylindole-2-carboxylic acid CCR2b chemokine receptor antagonists. These compounds demonstrate high affinity and functional inhibition of the CCR2b receptor. A discussion of
ANTI-INFLAMMATORY INDOLE DERIVATIVES
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, (2008/06/13)
Compounds of formula (I) or a pharmaceutically acceptable salt, in vivo hydrolysable ester, or an N-C1-6alkyl or N,N-di-(C1-6alkyl)amide thereof, where X is CH2 or SO2; R1 is an aryl optionally substituted by alkyl, alkenyl, alkynyl, halo, haloalkyl inclu
