220679-83-4Relevant academic research and scientific papers
Convergent synthesis of a fully phosphorylated GPI anchor of the CD52 antigen
Wu, Xiaoming,Guo, Zhongwu
, p. 4311 - 4313 (2007)
A fully phosphorylated GPI anchor (1) of the CD52 antigen was synthesized by a highly convergent strategy. After a trimannose and a phospholipidated pseudodisaccharkte were prepared separately, they were coupled together to form the GPI core, which was th
1,2-Diacetals in synthesis: Total synthesis of a glycosylphosphatidylinositol anchor of Trypanosoma brucei
Baeschlin, Daniel K.,Chaperon, Andre R.,Green, Luke G.,Hahn, Michael G.,Ince, Stuart J.,Ley, Steven V.
, p. 172 - 186 (2007/10/03)
A full account on a total synthesis of GPI anchor 1 employing butanediacetal (BDA) groups and a chiral bis(dihydropyran) is presented. The reactivity of selenium and thio glycosides was tuned by the use of BDA groups. This allowed the assembly of an appro
