220697-59-6

Upstream product

• 845616-98-0 tert-butyl 4-(4-(oxazol-2-yl)phenyl)piperazine-1-carboxylate 
• 176961-50-5 2-(4-bromophenyl)oxazole 

Downstream Products

• 1428536-37-1 2-(4-(4-(pyridin-3-ylmethyl)piperazin-1-yl)phenyl)oxazole 
• 1428536-38-2 2-(4-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl)phenyl)oxazole 
• 1428536-39-3 2-(4-(4-(thiophen-2-ylmethyl)piperazin-1-yl)phenyl)oxazole 

Relevant academic research and scientific papers

Discovery and preliminary structure-activity relationship of arylpiperazines as novel, brain-penetrant antiprion compounds

Creutzfeldt-Jakob disease and kuru in humans, BSE in cattle, and scrapie in sheep are fatal neurodegenerative disorders. Such illnesses are caused by the conversion and accumulation of a misfolded pathogenic isoform (termed PrP Sc) of a normall

Indole derivatives as 5-HT1B and 5-HT1D agonists

The invention concerns novel indole piperazine derivatives of Formula (I): It also concerns a method for preparing said compounds and their use as therapeutically active substances, in particular for treating or preventing diseases related to the dysfunct