220737-64-4Relevant academic research and scientific papers
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties
Hu, Lain-Yen,Ryder, Todd R.,Rafferty, Michael F.,Feng, M. Rose,Lotarski, Susan M.,Rock, David M.,Sinz, Michael,Stoehr, Sally J.,Taylor, Charles P.,Weber, Mark L.,Bowersox, S. Scott,Miljanich, George P.,Millerman, Elizabeth,Wang, Yong-Xiang,Szoke, Balazs G.
, p. 4239 - 4249 (2007/10/03)
In this article, the rationale for the design, synthesis, and biological evaluation of a series of N-type voltage-sensitive calcium channel (VSCC) blockers is described. N-Type VSCC blockers, such as ziconotide, have shown utility in several models of str
