220779-45-3

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 187682-17-3 -3-(4-(methoxycarbonyl)phenyl)-2-methylprop-2-enoic acid 
• 220778-86-9 tert-butyl 3-acetoxy-2-methylene-3-(4-(methoxycarbonyl)phenyl)propanoate 
• 878397-12-7 methyl 4-(3-bromo-2-tert-butoxycarbonylpropenyl)-benzoate 

Relevant academic research and scientific papers

NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention discloses novel naphthalenyloxypropenyl derivatives useful for inhibiting the enzyme activity of histone deacetylase, leading effective suppression of cancer cell proliferation

ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF

This invention discloses a novel arylaminomethyl propenyl benzhydroxyamide derivative of formula (I) useful for preventing or treating various diseases induced by histone deacetylase, a method for preparing same and a pharmaceutical composition comprising

A facile one-pot conversion of acetates of the Baylis-Hillman adducts to [E]-α-methylcinnamic acids

A simple and convenient stereoselective synthesis of [E]-α- methylcinnamic acids via the nucleophilic addition of hydride ion from sodium borohydride to methyl 3-acetoxy-3-aryl-2-methylenepropanoates followed by hydrolysis and crystallization is described