22081-35-2Relevant academic research and scientific papers
Trifluoroacetamides from amino alcohols as nucleophilic trifluoromethylating reagents
Joubert, Jerome,Roussel, Solveig,Christophe, Carole,Billard, Thierry,Langlois, Bernard R.,Vidal, Thierry
, p. 3133 - 3136 (2007/10/03)
Both non-enolizable and enolizable carbonyl compounds underwent nucleophilic trifluoromethylation by a new family of cheap and efficient trifluoroacetamide reagents derived from vic-amino alcohols (see picture). From an ecological and an economic viewpoint these represent a promising alternative to other known trifluoromethylation reagents.
