22083-48-3Relevant academic research and scientific papers
Pinacol reduction-cum-rearrangement. A re-examination of the reduction of aryl alkyl ketones by zinc-aluminum chloride
Grant, Anya A.,Allukian, Myron,Fry, Albert J.
, p. 4391 - 4393 (2002)
Reduction of alkyl phenyl ketones by zinc and aluminum chloride in acetonitrile results in pinacol condensation followed by rearrangement. The phenyl group migrates in every instance.
A one-pot cross-pinacol coupling/rearrangement procedure
Scheffler, Ulf,Mahrwald, Rainer
, p. 1970 - 1975,6 (2012/12/12)
A new catalytic retro-pinacol/cross-pinacol reaction, followed by subsequent rearrangement or deoxygenation of the intermediately formed vicinal diols, is described. This operationally simple one-pot protocol allows isolation of geminal α,α-diphenyl ketones or 1,1-diphenyl alkenes with high yields and selectivities. Copyright
Acid-catalyzed Reactions of 1,2-Dicarbonylethanes with Benzene. Ethylene Dication Electrophiles.
Yamazaki, Takahisa,Saito, Shin-ichi,Ohwada, Tomohiko,Shudo, Koichi
, p. 5749 - 5752 (2007/10/02)
1,2-dicarbonyl compounds reacted with benzene in the presence of a strong acid, trifluoromethanesulfonic acid, to give gem-diphenylated ketones in high yields.The reaction was accelerated when the acidity of the medium was increased, supporting involvement of O,O-diprotonated 1,2-dicarbonyl species (i.e., 1,2-dihydroxyethylene dications) as the active electrophiles.
