220841-51-0

Basic information

• Product Name: 4-(1-diazo-2-oxo-2-phenylethyl)-2-ethoxy-4-hydroxy-2-methyl-2-cyclobutenone
• Synonyms: 4-(1-diazo-2-oxo-2-phenylethyl)-2-ethoxy-4-hydroxy-2-methyl-2-cyclobutenone
• CAS NO: 220841-51-0
• Molecular Weight: 286.287
• Mol File: 220841-51-0.mol

Chemical Properties

• CAS DataBase Reference: 4-(1-diazo-2-oxo-2-phenylethyl)-2-ethoxy-4-hydroxy-2-methyl-2-cyclobutenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-diazo-2-oxo-2-phenylethyl)-2-ethoxy-4-hydroxy-2-methyl-2-cyclobutenone(220841-51-0)
• EPA Substance Registry System: 4-(1-diazo-2-oxo-2-phenylethyl)-2-ethoxy-4-hydroxy-2-methyl-2-cyclobutenone(220841-51-0)

Safety Data

• Hazardous Substances Data: 220841-51-0(Hazardous Substances Data)

Upstream product

• 3282-32-4 2-diazo-acetophenone 
• 75966-09-5 3-ethoxy-4-methyl-3-cyclobutene-1,2-dione 

Relevant articles and documents

Ring expansion of diazo-functionalized 4-hydroxycyclobutenone: Catalytic ring opening and recyclization to 2(5H)-furanone/cyclopentenedione and thermal 4π-8π electrocyclic ring opening-closure to diazepinedione

The acid-catalyzed and Rh-catalyzed (also photolyzed) decomposition of 4-hydroxycyclobutenones with a diazo group at C-4 gave 2(5H)-furanone and/or cyclopentene-1,3-dione via an α-carbocation intermediate and a carbenoid (carbene) intermediate, respectively. Thermal rearrangement of some of these compounds led to the formation of diazepinediones without the extrusion of nitrogen through tandem 4π electrocyclic ring opening and 8π electrocyclic ring closure processes.