220848-61-3Relevant academic research and scientific papers
Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: Confirmation of stereostructure by X-ray analysis
Li, Tingyou,Tsuda, Yuko,Minoura, Katsuhiko,In, Yasuko,Ishida, Toshimasa,Lazarus, Lawrence H.,Okada, Yoshio
, p. 873 - 877 (2006)
Six phenylalanine analogues containing 2′-methyl-, 2′,6′-dimethyl-, 2′-ethyl-6′-methyl-, 2′-isopropyl-6′-methyl-, 2′,4′,6′-trimethyl-, and 3′,5′-dimethyl-L-phenylalanine were synthesized enantioselectively through asymmetric hydrogenation of acetamidoacrylate derivatives. Enzymatic digestion and X-ray analysis supported the L-configuration of the phenylalanine derivatives obtained.
4-pyridinyl-n-acyl-l-phenylalanines
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, (2008/06/13)
Compounds of Formula I have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4 and are useful for treating disease whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4.
N-aroylphenylalanine derivative VCAM-1 inhibitors
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, (2008/06/13)
Compounds of the formula: are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expr
