5266-85-3

Basic information

• Product Name: 6-Isopropyl-o-toluidine
• Synonyms: 2-AMINO-M-CYMENE;2-METHYL-6-ISOPROPYLANILINE;2-METHYL-6-(1-METHYLETHYL)BENZENAMINE;2-ISOPROPYL-6-METHYLANILINE;AKOS BBS-00003625;6-ISOPROPYL-2-METHYLANILINE;6-ISOPROPYL-O-TOLUIDINE;TIMTEC-BB SBB004080
• CAS NO: 5266-85-3
• Molecular Formula: C₁₀H₁₅N
• Molecular Weight: 149.23
• EINECS: 226-083-5
• Mol File: 5266-85-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 231-232°C
• Flash Point: 42°C
• Appearance: clear red to brown liquid
• Density: 0,957 g/cm3
• Vapor Pressure: 0.048mmHg at 25°C
• Refractive Index: n20/D 1.544(lit.)
• PKA: 4.28±0.10(Predicted)
• CAS DataBase Reference: 6-Isopropyl-o-toluidine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Isopropyl-o-toluidine(5266-85-3)
• EPA Substance Registry System: 6-Isopropyl-o-toluidine(5266-85-3)

Safety Data

• Hazard Codes: Xn
• Statements: 10-20/21/22-36/37/38
• Safety Statements: 16-26-36/37/39-27
• RIDADR: 1993
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 5266-85-3(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR RED TO BROWN LIQUID

InChI:InChI=1/C10H15N/c1-7(2)9-6-4-5-8(3)10(9)11/h4-7H,11H2,1-3H3

Upstream product

• 187737-37-7 propene 
• 95-53-4 o-toluidine 
• 107859-36-9 2-methyl-6-(1-methylethenyl)benzenamine 
• 53848-17-2 2-bromo-6-methylaniline 

Downstream Products

• 97053-06-0 1-(2-Isopropyl-6-methyl-phenyl)-pyrrolidine 
• 140112-66-9 (Z)-Octadec-9-enoic acid (2-isopropyl-6-methyl-phenyl)-amide 
• 130403-12-2 3-Methyl-isoxazole-5-carboxylic acid (2-isopropyl-6-methyl-phenyl)-amide 
• 302958-03-8 [4-methyl-5-[[[2-methyl-6-(1-methylethyl)phenyl]-amino]carbonyl]-2-thiazolyl]carbamic acid 1,1-dimethylethyl ester 
• 545372-75-6 2-cyano-N-(2-isopropyl-6-methylphenyl)acetamide 
• 786677-15-4 2-isopropyl-6-methyl-benzonitrile 
• 307539-50-0 N-(2-Isopropyl-6-methylphenyl)-(2-chloro-5-nitrophenyl)carboxamide 
• 199592-88-6 6-bromo-N-(2-isopropyl-6-methylphenyl)hexanamide 
• 330433-98-2 [MoCl₂(NCC₆H₃Me-2-i-Pr-6)2(dme)] 
• 773887-09-5 5-bromo-7-isopropyl-1H-indazole 

Relevant articles and documents

Pyridopyrimidinone compound and application thereof

The invention provides a pyridopyrimidinone compound with a structure as shown in a general formula (II) and application thereof. Researches prove that the compound provided by the invention can effectively inhibit KRAS G12C mutation. KRAS mutation accounts for a large proportion in tumors, no approved drug is obtained for treatment at present, and the compound provided by the invention has the potential to become a therapeutic drug for malignant tumors (especially non-small cell lung cancer (NSCLC) and colorectal cancer) carrying KRAS G12C mutation, and has a great application value.