220854-79-5

Basic information

• Product Name: (Z)-2-Benzyloxycarbonylamino-3-pyridin-2-yl-acrylic acid methyl ester
• Synonyms: (Z)-2-Benzyloxycarbonylamino-3-pyridin-2-yl-acrylic acid methyl ester
• CAS NO: 220854-79-5
• Molecular Weight: 312.325
• Mol File: 220854-79-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-2-Benzyloxycarbonylamino-3-pyridin-2-yl-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Benzyloxycarbonylamino-3-pyridin-2-yl-acrylic acid methyl ester(220854-79-5)
• EPA Substance Registry System: (Z)-2-Benzyloxycarbonylamino-3-pyridin-2-yl-acrylic acid methyl ester(220854-79-5)

Safety Data

• Hazardous Substances Data: 220854-79-5(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 1191124-96-5 N-benzyloxycarbonyl-α-(diphenylphosphono)glycine methyl ester 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 114684-69-4 methyl 2-(benzyloxycarbonylamino)-2-(diethyloxyphosphoryl)acetate 

Downstream Products

• 372520-48-4 (S)-2-Benzyloxycarbonylamino-3-(1-oxy-pyridin-2-yl)-propionic acid methyl ester 

Relevant articles and documents

Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine.

[reaction: see text] A novel method for the synthesis of (2-pyridyl)alanines 2a-b was developed by converting (2-pyridyl)dehydroamino acid derivatives 1a-b to the corresponding N-oxides 3a-b followed by asymmetric hydrogenation using (R,R)-[Rh(Et-DUPHOS)(

Preparation of (S)-2-quinolylalanine by asymmetric hydrogenation

The synthesis of (S)-2-quinolylalanine through asymmetric hydrogenation with (S,S)-Et-DuPHOS-Rh is described. The reaction has been extended to other 2-pyridylalanine derivatives.