22087-22-5

Basic information

• Product Name: [2-(4-CHLORO-PHENYL)-OXAZOL-4-YL]-METHANOL
• Synonyms: [2-(4-CHLORO-PHENYL)-OXAZOL-4-YL]-METHANOL;4-Oxazolemethanol, 2-(4-chlorophenyl)-
• CAS NO: 22087-22-5
• Molecular Formula: C₁₀H₈ClNO₂
• Molecular Weight: 209.63
• Mol File: 22087-22-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [2-(4-CHLORO-PHENYL)-OXAZOL-4-YL]-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-CHLORO-PHENYL)-OXAZOL-4-YL]-METHANOL(22087-22-5)
• EPA Substance Registry System: [2-(4-CHLORO-PHENYL)-OXAZOL-4-YL]-METHANOL(22087-22-5)

Safety Data

• Hazardous Substances Data: 22087-22-5(Hazardous Substances Data)

Usage

General Description

[2-(4-chloro-phenyl)-oxazol-4-yl]-methanol is a chemical compound that is a derivative of oxazole, a five-membered heterocyclic aromatic organic compound containing nitrogen, oxygen, and carbon atoms in its ring. The compound contains a methanol group attached to the oxazole ring, and a 4-chloro-phenyl group attached to the second position of the oxazole ring. It is used in organic synthesis and pharmaceutical research as a building block for the preparation of various biologically active compounds. Additionally, it may have potential applications in medicinal chemistry and drug development due to its structural features and functional groups. However, further research is needed to fully elucidate its potential uses and properties.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 300800-07-1 methyl 2-(4-chlorophenyl)-1,3-oxazole-4-carboxylate 
• 619-56-7 4-chlorobenzamide 
• 22091-36-7 4-chloromethyl-2-(4-chlorophenyl)oxazole 

Downstream Products

• 36841-60-8 [5-bromo-2-(4-chloro-phenyl)-oxazol-4-yl]-methanol 
• 59398-91-3 2-(4-chloro-phenyl)-oxazole-4-carbaldehyde 
• 22091-36-7 4-chloromethyl-2-(4-chlorophenyl)oxazole 
• 1198212-13-3 2-{[2-(4-Chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-[4-(2-hydroxyethoxy)phenyl]-6-methoxypyridine-3,5-dicarbonitrile 
• 1325717-69-8 Methyl 2-(4-chlorophenyl)-4-(hydroxymethyl)-1,3-oxazole-5-carboxylate 
• 1325717-68-7 Methyl 2-(4-chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole-5-carboxylate 
• 1325717-58-5 2-(4-Chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole-5-carboxylic acid 
• 1325717-56-3 2-(4-Chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole-5-carbaldehyde 
• 1325717-55-2 2-(4-Chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole 
• 1107662-79-2 2-Amino-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-[4-(2-hydroxyethoxy)phenyl]-pyridine-3,5-dicarbonitrile 
• 1107662-78-1 2-Amino-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-(4-{[(2R)-2,3-dihydroxypropyl]oxy}phenyl)pyridine-3,5-dicarbonitrile 
• 1107663-70-6 2-Amino-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-(4-{[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}phenyl)pyridine-3,5-dicarbonitrile 

Relevant articles and documents

2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS

The present invention relates to benzimidazole derivatives having the general formula I, wherein n is 0 or 1; X1 and X2 are independently, at each occurrence, CR5 or N; Y is C1-C6 alkylene, wherein alkylene is optionally substituted with one to two C1-C3 alkyl groups; R1 is selected from the group consisting of hydrogen, halogen, C1-C6 alkoxy, -NH2, -NHR6, -NR7R8 and -NH-(R9)n-R10, n being 0 or 1; R2 is selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, -NH2, -NHR6, - NR7R8 and -NH-(R9)n-R10; R3 is selected from the group consisting of hydrogen, hydroxyl, OR11, -NR7R8, C1-C6 alkoxy, C1-C6 alkyl, C3-C10 cycloalkyl, C1-C3 haloalkyl, -C(O)NHR11, aryl, heteroaryl and heterocyclyl, wherein each of said cycloalkyl, aryl, heteroaryl and heterocyclyl is optionally and independently substituted with one to four Ra groups; and R4 is selected from the group consisting of -NH2, -N(R12)(V)pR13, - NH(V)p-OR14, -NHC(O)R15, and groups of formula la shown below, and their use in the treatment of diseases, in particular inflammatory diseases, cancer, stroke and/or Alzheimer's disease.

2-ALKOXY-SUBSTITUTED DICYANOPYRIDINES AND THEIR USE

The present application relates to novel 2-alkoxy-substituted dicyanopyridines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders.

Nitration and halogenation of various 2-aryl-4-chloro-methyl-oxazoles. 23. Heterocyclic compounds

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