59398-91-3

Basic information

• Product Name: 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE
• Synonyms: 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE;4-Oxazolecarboxaldehyde, 2-(4-chlorophenyl)-
• CAS NO: 59398-91-3
• Molecular Formula: C₁₀H₆ClNO₂
• Molecular Weight: 207.61
• Mol File: 59398-91-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE(59398-91-3)
• EPA Substance Registry System: 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE(59398-91-3)

Safety Data

• Hazardous Substances Data: 59398-91-3(Hazardous Substances Data)

Usage

General Description

2-(4-chloro-phenyl)-oxazole-4-carbaldehyde is a chemical compound with the molecular formula C10H6ClNO2. It is an oxazole derivative containing a 4-chlorophenyl group and a carbaldehyde functional group. 2-(4-CHLORO-PHENYL)-OXAZOLE-4-CARBALDEHYDE has potential applications in the fields of pharmaceuticals and organic synthesis. It can be used as a building block in the synthesis of various biologically active molecules and pharmaceutical intermediates. Its unique structure and properties make it a valuable tool for researchers and chemists working in the field of drug discovery and development.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 22087-22-5 [2-(4-chloro-phenyl)-oxazol-4-yl]-methanol 
• 300800-07-1 methyl 2-(4-chlorophenyl)-1,3-oxazole-4-carboxylate 
• 26086-60-2 2-azido-4'-chloroacetophenone 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 22091-36-7 4-chloromethyl-2-(4-chlorophenyl)oxazole 

Downstream Products

• 59398-96-8 5-bromo-2-(4-chloro-phenyl)-oxazole-4-carbaldehyde 

Relevant articles and documents

2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS

The present invention relates to benzimidazole derivatives having the general formula I, wherein n is 0 or 1; X1 and X2 are independently, at each occurrence, CR5 or N; Y is C1-C6 alkylene, wherein alkylene is optionally substituted with one to two C1-C3 alkyl groups; R1 is selected from the group consisting of hydrogen, halogen, C1-C6 alkoxy, -NH2, -NHR6, -NR7R8 and -NH-(R9)n-R10, n being 0 or 1; R2 is selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, -NH2, -NHR6, - NR7R8 and -NH-(R9)n-R10; R3 is selected from the group consisting of hydrogen, hydroxyl, OR11, -NR7R8, C1-C6 alkoxy, C1-C6 alkyl, C3-C10 cycloalkyl, C1-C3 haloalkyl, -C(O)NHR11, aryl, heteroaryl and heterocyclyl, wherein each of said cycloalkyl, aryl, heteroaryl and heterocyclyl is optionally and independently substituted with one to four Ra groups; and R4 is selected from the group consisting of -NH2, -N(R12)(V)pR13, - NH(V)p-OR14, -NHC(O)R15, and groups of formula la shown below, and their use in the treatment of diseases, in particular inflammatory diseases, cancer, stroke and/or Alzheimer's disease.

Sommelet reaction with 2 aryl 4 chlormethyl oxazoles

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