2209-00-9Relevant academic research and scientific papers
Highly E-selective solvent-free Horner-Wadsworth-Emmons reaction catalyzed by DBU
Ando, Kaori,Yamada, Kyohei
supporting information; experimental part, p. 1143 - 1146 (2011/06/24)
The solvent-free Horner-Wadsworth-Emmons reaction of triethyl phosphonoacetate with a variety of aldehydes was catalyzed by DBU in the presence of K2CO3 to give E-α,β-unsaturated esters highly selectively (99:1 for most of the reactions). The reaction with ketones gave trisubstituted olefins with good to high E-selectivity by DBU-Cs2CO3.
Construction of a quaternary carbon at the carbonyl carbon of the cyclohexane ring
Kaneko, Yuki,Kiyotsuka, Yohei,Acharya, Hukum P.,Kobayashi, Yuichi
supporting information; experimental part, p. 5482 - 5484 (2010/10/04)
High SN2′ selectivity in the allylic substitution of cyclohexylidene ethyl picolinates with copper reagents prepared from RMgBr and CuBr·Me2S was realized by addition of ZnX2 (X = I, Br, Cl). Furthermore, ZnX2 accelerated the reaction with the bulky iPr reagent. The Royal Society of Chemistry 2010.
STEREOSELECTIVE PETERSON ALKOXYCARBONYLMETHYLENATION REACTION OF SUBSTITUTED CYCLOHEXANONES
Strekowski, Lucjan,Visnick, Melean,Battiste, Merle A.
, p. 5603 - 5606 (2007/10/02)
In contrast to previous results the Peterson olefination reaction of substituted cyclohexanones with metallotrimethylsilylacetates (1) affords moderate to high stereoselectivity.
