220910-37-2

Upstream product

• 220910-35-0 (S)-3-[4-(6-tert-Butoxycarbonylamino-hexyloxy)-phenyl]-2-(3-phenyl-propionylamino)-propionic acid 2-((Z)-3-oxo-propenyl)-phenyl ester 
• 142355-89-3 (S)-3-[4-(6-tert-Butoxycarbonylamino-hexyloxy)-phenyl]-2-(3-phenyl-propionylamino)-propionic acid 
• 185995-96-4 (Z)-2-(3-(tert-butyldimethylsilyloxy)propenyl)phenol 
• 220910-33-8 (S)-3-[4-(6-tert-Butoxycarbonylamino-hexyloxy)-phenyl]-2-(3-phenyl-propionylamino)-propionic acid 2-((Z)-3-hydroxy-propenyl)-phenyl ester 
• 220910-31-6 3-[4-(6-tert-butoxycarbonylamino-hexyloxy)-phenyl]-2-(3-phenyl-propionylamino)-propionic acid 2-[3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-phenyl ester 

Relevant academic research and scientific papers

Synthesis and evaluation of novel coumarin-based esterase-sensitive cyclic prodrugs of peptidomimetic RGD analogs with improved membrane permeability

Earlier, we reported the development of a coumarin-based prodrug system that could be used for the preparation of cyclic prodrugs of opioid peptides. These cyclic prodrugs exhibited excellent membrane permeability characteristics. Therefore, it was of int