220966-22-3Relevant academic research and scientific papers
Synthesis of isoindolo[1,3]benzoxazine derivatives through intramolecular arylation of N-acyliminium ions
Hucher, Nicolas,Daich, Adam,Decroix, Bernard
, p. 1477 - 1483 (1998)
[1,3]Benzoxazines annulated to isoindole as 3 and 4 have been synthesized in three steps from N-chloromethylphthalimide 5 and substituted phenols 6. The key step was the acid-catalyzed cyclization of ω-carbinol lactams 8 and 9.
