Journal of Heterocyclic Chemistry p. 1477 - 1483 (1998)
Update date:2022-08-03
Topics:
Hucher, Nicolas
Daich, Adam
Decroix, Bernard
[1,3]Benzoxazines annulated to isoindole as 3 and 4 have been synthesized in three steps from N-chloromethylphthalimide 5 and substituted phenols 6. The key step was the acid-catalyzed cyclization of ω-carbinol lactams 8 and 9.
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