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220996-36-1

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220996-36-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 220996-36-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,9,9 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 220996-36:
(8*2)+(7*2)+(6*0)+(5*9)+(4*9)+(3*6)+(2*3)+(1*6)=141
141 % 10 = 1
So 220996-36-1 is a valid CAS Registry Number.

220996-36-1Downstream Products

220996-36-1Relevant articles and documents

Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors

Smith, Aaron L.,Freeman, Sara M.,Stehouwer, Jeffery S.,Inoue, Kiyoshi,Voll, Ronald J.,Young, Larry J.,Goodman, Mark M.

experimental part, p. 2721 - 2738 (2012/05/20)

Compounds 1-4 were synthesized and investigated for selectivity and potency for the oxytocin receptor (OTR) to determine their viability as radioactive ligands. Binding assays determined 1-4 to have high binding affinity for both the human and rodent OTR

Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency

Williams, Peter D.,Bock, Mark G.,Evans, Ben E.,Freidinger, Roger M.,Gallicchio, Steven N.,Guidotti, Maribeth T.,Jacobson, Marlene A.,Michelle S, Kuo,Levy, Michelle R.,Edward V, Lis,Michelson, Stuart R.,Pawluczyk, Joseph M.,Perlow, Debra S.,Pettibone, Douglas J.,Quigley, Amy G.,Reiss, Duane R.,Salvatore, Christopher,Stauffer, Kenneth J.,Woyden, Carla J.

, p. 1311 - 1316 (2007/10/03)

Structure-activity studies on the oxytocin antagonist 1 (L-371,257; K(i) = 9.3 nM) have led to the identification of a related series of compounds containing an ortho-trifluoroethoxyphenylacetyl core which are orally bioavailable and have significantly improved potency in vitro and in vivo, e.g., compound 8 (L-374,943; K(i) = 1.4 nM).

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