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4-(N,N-Diethylaminomethyl)benzeneboronic acid is a boronic acid derivative characterized by a benzene ring with a diethylaminomethyl group and a boronic acid functional group. It is recognized for its capacity to form stable complexes with various nucleophiles, such as diols and amino alcohols, which makes it a versatile reagent in organic synthesis and medicinal chemistry. Its applications extend to the development of pharmaceuticals, agrochemicals, and materials science, often serving as a building block for synthesizing more complex organic molecules. Moreover, its distinctive properties render it a valuable asset in chemical biology and drug discovery research.

220999-48-4

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220999-48-4 Usage

Uses

Used in Organic Synthesis:
4-(N,N-Diethylaminomethyl)benzeneboronic acid is used as a reagent in organic synthesis for its ability to form stable complexes with nucleophiles, facilitating Suzuki–Miyaura cross-coupling reactions and other carbon-carbon bond forming processes.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-(N,N-Diethylaminomethyl)benzeneboronic acid is utilized as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Development:
4-(N,N-Diethylaminomethyl)benzeneboronic acid is employed in the agrochemical industry for the synthesis of compounds with pesticidal or herbicidal properties, enhancing crop protection and yield.
Used in Materials Science:
In materials science, 4-(N,N-Diethylaminomethyl)benzeneboronic acid is used as a component in the creation of new materials with specific properties, such as those with enhanced stability or reactivity.
Used in Chemical Biology and Drug Discovery Research:
4-(N,N-Diethylaminomethyl)benzeneboronic acid is used as a tool in chemical biology and drug discovery, where its unique properties aid in the exploration of new biochemical pathways and the identification of potential drug targets.

Check Digit Verification of cas no

The CAS Registry Mumber 220999-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,9,9 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 220999-48:
(8*2)+(7*2)+(6*0)+(5*9)+(4*9)+(3*9)+(2*4)+(1*8)=154
154 % 10 = 4
So 220999-48-4 is a valid CAS Registry Number.

220999-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(diethylaminomethyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names OR7198

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:220999-48-4 SDS

220999-48-4Downstream Products

220999-48-4Relevant academic research and scientific papers

The characterization of a novel V1b antagonist lead series

Smethurst, Chris A.,Borthwick, Jennifer A.,Gaines, Simon,Watson, Steve,Green, Andrew,Schulz, Mark J.,Burton, George,Buson, Alberto A.,Arban, Roberto

scheme or table, p. 92 - 96 (2011/02/28)

The SAR around a V1b antagonist HTS hit 3 was explored to produce a series of thiazole sulfonamides as a lead series with selectivity over the related V1 and oxytocin receptors.

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