2210-63-1 Usage
Uses
Used in Pharmaceutical Industry:
Mofebutazone is used as an anti-inflammatory agent for the treatment of joint and muscular pain. Its efficacy in reducing inflammation and pain is attributed to its ability to alleviate discomfort and promote healing in affected areas.
Additionally, Mofebutazone is used as a protective agent for gastrointestinal and renal tissues. This application is particularly important in managing the side effects often associated with anti-inflammatory drugs, ensuring the safety and well-being of patients undergoing treatment.
Brand names of Mofebutazone include Arcobutine, Buta lyseen, Chemiartrol, Clinit, Diadin, Fenartril, Jovapyrin, Mobutazone, Mofasal, Mofeasal, Monazone, Monbutina, Monobutina, Monofen, Monomil, Monoprine, Monozon, Mozol, Rheuma-cur, Rheumaorctat, Rivodol, and Sodepyrine B 1, reflecting its widespread use and recognition across different markets and healthcare settings.
Originator
Butaphen,Wiedenmann
Manufacturing Process
A mixture comprising 108 g of phenyl hydrazine and 216 g of the diethyl ester
of n-butylmalonic acid is heated on an oil bath at 170°-180°C for 12 hours.
The residue is taken up with water in which an alkaline compound has been
dissolved and acetic acid is added to precipitate 4-n-butyl-2-phenylpyrazolidine-3,5-dione. The product is a white crystalline solid having a MP:
103°C. It is soluble in acetone and benzene, soluble in hot condition in
methanol and ethanol and insoluble in water.
Therapeutic Function
Antirheumatic, Analgesic, Antiinflammatory
World Health Organization (WHO)
Mofebutazone, a pyrazolone with anti-inflammatory, analgesic
and antipyretic activity, was introduced in 1962 for the treatment of rheumatic
disorders. As it is structurally related to phenylbutazone it is subjected to
rigorously restricted indications by some national regulatory authorities. See WHO
comment for phenylbutazone.
Check Digit Verification of cas no
The CAS Registry Mumber 2210-63-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,1 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2210-63:
(6*2)+(5*2)+(4*1)+(3*0)+(2*6)+(1*3)=41
41 % 10 = 1
So 2210-63-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O2/c1-2-3-9-11-12(16)14-15(13(11)17)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3,(H,14,16)
