2210-63-1 Usage
Originator
Butaphen,Wiedenmann
Uses
Mofebutazone is an anti-inflammatory drug used on the gastrointestinal and renal tissues.
Definition
ChEBI: A pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain.
Manufacturing Process
A mixture comprising 108 g of phenyl hydrazine and 216 g of the diethyl ester
of n-butylmalonic acid is heated on an oil bath at 170°-180°C for 12 hours.
The residue is taken up with water in which an alkaline compound has been
dissolved and acetic acid is added to precipitate 4-n-butyl-2-phenylpyrazolidine-3,5-dione. The product is a white crystalline solid having a MP:
103°C. It is soluble in acetone and benzene, soluble in hot condition in
methanol and ethanol and insoluble in water.
Brand name
Arcobutine;Buta lyseen;Chemiartrol;Clinit;Diadin;Fenartril;Jovapyrin;Mobutazone;Mofasal;Mofesal;Monazone;Monbutina;Monobutina;Monofen;Monomil;Monoprine;Monozon;Mozol;Rheuma-cur;Rheumaorctat;Rivodol;Sodepyrine b 1.
Therapeutic Function
Antirheumatic, Analgesic, Antiinflammatory
World Health Organization (WHO)
Mofebutazone, a pyrazolone with anti-inflammatory, analgesic
and antipyretic activity, was introduced in 1962 for the treatment of rheumatic
disorders. As it is structurally related to phenylbutazone it is subjected to
rigorously restricted indications by some national regulatory authorities. See WHO
comment for phenylbutazone.
Check Digit Verification of cas no
The CAS Registry Mumber 2210-63-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,1 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2210-63:
(6*2)+(5*2)+(4*1)+(3*0)+(2*6)+(1*3)=41
41 % 10 = 1
So 2210-63-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O2/c1-2-3-9-11-12(16)14-15(13(11)17)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3,(H,14,16)
