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4-BROMO-3-METHYLPHENYLBORONIC ACID, with the molecular formula C7H8BBrO2, is a chemical compound that features a boronic acid functional group. This group endows it with significant utility in organic synthesis, particularly as a building block for constructing complex molecules. Known for its stability as a white solid under normal conditions, it is typically handled and stored under an inert atmosphere to avert degradation. Its versatility in the Suzuki-Miyaura cross-coupling reaction, a widely used method for creating carbon-carbon bonds, further underscores its importance in the realms of medicinal chemistry and material science.

221006-67-3

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221006-67-3 Usage

Uses

Used in Medicinal Chemistry:
4-BROMO-3-METHYLPHENYLBORONIC ACID is used as a synthetic intermediate for the development of pharmaceutical compounds, leveraging its reactivity in cross-coupling reactions to form diverse molecular structures that can exhibit therapeutic properties.
Used in Material Science:
In the field of material science, 4-BROMO-3-METHYLPHENYLBORONIC ACID is used as a precursor for the synthesis of advanced materials, contributing to the creation of new substances with unique electronic, optical, or mechanical properties.
Used in the Suzuki-Miyaura Cross-Coupling Reaction:
4-BROMO-3-METHYLPHENYLBORONIC ACID is utilized as a key reagent in the Suzuki-Miyaura cross-coupling reaction, a method pivotal for forming carbon-carbon bonds in organic synthesis, thereby facilitating the construction of complex organic molecules with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 221006-67-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,0,0 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 221006-67:
(8*2)+(7*2)+(6*1)+(5*0)+(4*0)+(3*6)+(2*6)+(1*7)=73
73 % 10 = 3
So 221006-67-3 is a valid CAS Registry Number.

221006-67-3Upstream product

221006-67-3Relevant academic research and scientific papers

Synthesis of new phenylpyridyl scaffolds using the Garlanding approach

Voisin-Chiret, Anne Sophie,Muraglia, Marilena,Burzicki, Grégory,Perato, Serge,Corbo, Filomena,Sopková-De Oliveira Santos, Jana,Franchini, Carlo,Rault, Sylvain

experimental part, p. 8000 - 8005 (2010/10/21)

One-pot reaction for the synthesis of novel phenylpyridyl derivatives and mixed quater phenylpyridyl compounds is described by using the Garlanding approach. The reactions proceed with moderate to good yields in mild conditions and good reaction times. This work represents a second application of the simplicity and versatility of Garlanding concept for the construction of new phenylpyridyl scaffolds, which can be considered as non-peptidic foldamer α-helix mimetics.

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