92022-07-6

Usage

Uses

Used in Organic Synthesis:
4-BROMO-3'-METHYLBIPHENYL is utilized as a building block in organic synthesis for the creation of various organic molecules. Its unique structure allows it to be a key component in the formation of complex organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, 4-BROMO-3'-METHYLBIPHENYL serves as a valuable intermediate for the synthesis of pharmaceutical compounds. Its presence in these compounds can contribute to their efficacy and therapeutic potential.
Used in Dye Production:
4-BROMO-3'-METHYLBIPHENYL is employed as a reagent in the production of dyes. Its chemical properties make it suitable for the development of dyes with specific characteristics, such as color intensity and stability.
Used in Optoelectronic Material Production:
4-BROMO-3'-METHYLBIPHENYL also finds use in the production of optoelectronic materials, where its structural features can enhance the performance of these materials in various electronic applications.
Used in Biological Research:
4-BROMO-3'-METHYLBIPHENYL has been studied for its potential biological activities, including its role as a potential anti-tumor agent. Its interaction with enzymes and receptors in the human body is of interest for developing new therapeutic approaches.
Used in Enzyme and Receptor Interaction Studies:
In biological research, 4-BROMO-3'-METHYLBIPHENYL is used to study its interactions with certain enzymes and receptors. Understanding these interactions can provide insights into its potential as a therapeutic agent and contribute to the development of new drugs.

Upstream product

• 6933-10-4 amino-5-bromo-2-toluene 
• 63019-98-7 3-methylbiphenyl-4-amine 
• 24106-05-6 4'-bromo-2'-methylacetanilide 
• 63040-30-2 N-(3-methyl-biphenyl-4-yl)-acetamide 
• 108-86-1 bromobenzene 
• 221006-67-3 1-bromo-2-methyl-4-phenylboronic acid 
• 202865-85-8 1-bromo-4-iodo-2-methylbenzene 
• 98-80-6 phenylboronic acid 
• 583-75-5 4-Bromo-2-methylaniline 

Downstream Products

• 162583-27-9 C₆H₅C₆H₃(CH₃)C₃BO₂H₄(CH₃)2 
• 1234887-19-4 1-(2-methyl-5-phenyl-3-thienyl)-2-(2-methyl-4-phenyl-1-phenyl)perfluorocyclopentene 
• 1400742-95-1 C₂₀H₂₄BBrO₂ 

Relevant academic research and scientific papers

Benzylic C?H Functionalisation by [Et3SiH+KOtBu] leads to Radical Rearrangements in o-tolyl Aryl Ethers, Amines and Sulfides

Reaction of Et3SiH+KOtBu with diaryl ethers, sulfides and amines that feature an ortho alkyl group leads to rearrangement products. The rearrangements arise from formation of benzyl radicals, likely formed through hydrogen atom abstraction by triethylsilyl radicals. The rearrangements involve cyclisation of the benzyl radical onto the partner arene, which, from computation, is the rate determining step. In the case of diaryl ethers, Truce-Smiles rearrangements arise from radical cyclisations to form 5-membered rings, but for diarylamines, cyclisations to form dihydroacridines are observed. (Figure presented.).

Copper-catalyzed recycling of halogen activating groups via 1,3-halogen migration

A Cu(I)-catalyzed 1,3-halogen migration reaction effectively recycles an activating group by transferring bromine or iodine from a sp2 to a benzylic carbon with concomitant borylation of the Ar-X bond. The resulting benzyl halide can be reacted in the same vessel under a variety of conditions to form an additional carbon-heteroatom bond. Cross-over experiments using an isotopically enriched bromide source support intramolecular transfer of Br. The reaction is postulated to proceed via a Markovnikov hydrocupration of the o-halostyrene, oxidative addition of the resulting Cu(I) complex into the Ar-X bond, reductive elimination of the new sp3 C-X bond, and final borylation of an Ar-Cu(I) species to turn over the catalytic cycle.

The synthesis of novel photochromic diarylethenes bearing a biphenyl moiety and the effects of substitution on their properties

A new class of diarylethene bearing a biphenyl moiety was synthesized and the effects of substitution on photochromism, fluorescence and electrochemical character, were investigated. Under alternating irradiation with UV and visible light, the compounds exhibited good photochromism and functioned as?fluorescent photoswitches both in solution and in PMMA film. Electron-donating substituents shifted the λmax of the diarylethenes to longer wavelengths and decreased their cyclization quantum yield, while electron-withdrawing substituents greatly increased both cyclization and cycloreversion quantum yield. In addition, cyclic voltammetry revealed that the substituents had a significant effect on the electrochemical behaviour of the diarylethene derivatives.

Synthesis of Sugar-containing Polymers by Self-condensation with Diboronic Acid

Self-condensation of 3,3'-bis(N,N-di-n-butylaminomethyl)biphenyl-4,4'-diboronic acid and saccharides yields polymers containing saccharides in the main chain: they show unique CD spectroscopic porperties which reflect the chirality of saccharides.