22101-21-9Relevant articles and documents
Synthesis of acrylonitriles through an FeCl3-catalyzed domino propargylic substitution/aza-Meyer-Schuster rearrangement sequence
Hao, Lu,Wu, Feng,Ding, Zong-Cang,Xu, Su-Xia,Ma, Yan-Li,Chen, Li,Zhan, Zhuang-Ping
supporting information; experimental part, p. 6453 - 6456 (2012/06/15)
Nontoxic cyanide source: An unprecedented route to acrylonitriles by employing propargylic alcohols and para-tolylsulfonohydrazide as a combined cyano source has been developed (see scheme). This efficient and practical cyanation reaction proceeds through an FeCl3-catalyzed domino propargylic substitution/aza-Meyer-Schuster rearrangement sequence, the rearrangement process of which is reported for the first time. Copyright
Role of water and phase transfer catalysts in the kinetics of condensation of diaryl ketones with acetonitrile initiated by solid potassium hydroxide
Bentley, T. William,Jones, Ray V. H.,Larder, Annette H.,Lock, Stephen J.
, p. 89 - 94 (2007/10/03)
The kinetics of reactions of benzophenone and substituted derivatives with acetonitrile in the presence of excess solid potassium hydroxide (KOH) to give 2,2-diarylacrylonitriles are reported. Reaction rates are strongly temperature dependent, and water,