221012-47-1

Upstream product

• 221012-46-0 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-(quinolin-2-ylsulfanyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 159721-72-9 3'-deoxy-3'-thio-3'-S-benzoyl-5'-O-(tert-butyldimethylsilyl)thymidine 
• 166955-24-4 5'-O-(tert-butyldimethylsilyl)-2,3'-anhydrothymidine 
• 101527-40-6 5'-O-tert-butyldiphenylsilylthymidine 
• 221012-41-5 1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(quinolin-2-ylsulfanyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 

Downstream Products

• 221012-48-2 C₄₆H₅₁N₅O₈S₂Si 
• 926656-50-0 1-[5-tert-butyldiphenylsilyl-2,3-dideoxy-3-thio-3-S-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-β-D-ribofuranosyl]-thymine 
• 926656-51-1 1-[2,3-dideoxy-3-thio-3-S-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-β-D-ribofuranosyl]-thymine 

Relevant academic research and scientific papers

Incorporation of a S-glycosidic linkage into a glyconucleoside changes the conformational preference of both furanose sugars

A glyconucleoside containing a thioglycoside linkage, namely 1-(3-S-β-d-ribofuranosyl-2,3-dideoxy-3-thio-β-d-ribofuranosyl)-thymine, has been prepared through condensation of a suitably protected derivative of 3′-thiothymidine with an activated ribose sug

A novel thiol protecting group: A 2-thioquinoline sulfide as a masked sulfhydryl moiety

2-Thioquinoline sulfide was developed as a masked sulfhydryl entity. It is introduced through facile S(N)2 displacement reactions and is stable to a variety of reaction conditions including acids, bases and nucleophiles. It is readily unmasked using the mild treatment of sodium cyanoborohydride in acetic acid.