22102-68-7

Basic information

• Product Name: N-(Hexacosanoyloxy)succinimide
• Synonyms: N-(Hexacosanoyloxy)succinimide;1-[(1-Oxohexacosyl)oxy]-2,5-pyrrolidinedione;Hexacosanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester;(2,5-Dioxopyrrolidin-1-yl)hexacosanoate
• CAS NO: 22102-68-7
• Molecular Formula: C₃₀H₅₅NO₄
• Molecular Weight: 493.762
• Product Categories: Aliphatics;Heterocycles;Aliphatics, Heterocycles
• Mol File: 22102-68-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 85.5-86.5 °C
• Boiling Point: 568.9±33.0 °C(Predicted)
• Appearance: /
• Density: 0.98±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly)
• CAS DataBase Reference: N-(Hexacosanoyloxy)succinimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(Hexacosanoyloxy)succinimide(22102-68-7)
• EPA Substance Registry System: N-(Hexacosanoyloxy)succinimide(22102-68-7)

Safety Data

• Hazardous Substances Data: 22102-68-7(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

N-(Hexacosanoyloxy)succinimide (cas# 22102-68-7) is a compound useful in organic synthesis.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 506-46-7 1-hexacosanoic acid 
• 1892-57-5 N-(3-dimethylaminopropyl)-N-ethylcarbodiimide 

Downstream Products

• 4201-58-5 (2S,3R,4E)-2-(hexadecanoylamido)-4-octadecene-1,3-diol 

Relevant articles and documents

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues

A synthesis strategy for the swift generation of 4″-modified α-galactosylceramide (α-GalCer) analogues is described, establishing a chemical platform to comprehensively investigate the structure-activity relationships (SAR) of this understudied glycolipid

PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3

The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae, and more specifically against diseases associated with Streptococcus pneumoniae type 3.

Synthesis and biological activities of 5-thio-α-GALCERS

NKT cells, a unique subset of T cells that recognizes glycolipid antigens presented by CD1d molecules, are believed to produce key cytokines of both Th1 and Th2 T cells and are thus involved in the control of several types of immune response. As an active glycolipid antigen having α-galactosyl ceramide core structure, KRN7000 showed promising immunostimulation activity and was selected as an anticancer drug candidate for further clinical application. In this report, three new KRN7000 structural analogues were designed and synthesized, in which the ring oxygen of the galactopyranose residue is replaced by a sulfur atom along with the variation on the lipid chain. Their abilities for stimulating mouse NKT cells to produce IFN-γ and IL-4 were evaluated both in vivo and in vitro.