22112-78-3

Usage

Uses

Used in Supramolecular Chemistry:
5,10,15,20-TETRAKIS(4-METHOXYPHENYL)-21H,23H-PORPHINE is used as a building block for constructing chiral supramolecular assemblies. Its ability to form chiral structures at the air or water interface makes it a valuable component in the development of new materials and systems with unique properties and functions.
Used in Material Science:
5,10,15,20-TETRAKIS(4-METHOXYPHENYL)-21H,23H-PORPHINE is used as a key component in the synthesis of advanced materials with specific optical, electronic, or catalytic properties. The chiral nature of its supramolecular assemblies can lead to novel material properties and applications.
Used in Pharmaceutical Industry:
5,10,15,20-TETRAKIS(4-METHOXYPHENYL)-21H,23H-PORPHINE is used as a potential candidate for drug development, particularly in the area of chiral pharmaceuticals. The unique properties of its supramolecular assemblies can be harnessed to improve drug delivery, selectivity, and efficacy.
Used in Analytical Chemistry:
5,10,15,20-TETRAKIS(4-METHOXYPHENYL)-21H,23H-PORPHINE is used as a chiral selector or sensing element in analytical techniques such as chromatography, capillary electrophoresis, and spectroscopy. Its ability to form chiral supramolecular assemblies can enhance the separation and detection of enantiomers in complex samples.

InChI:InChI=1/C48H38N4O4/c1-53-33-13-5-29(6-14-33)45-37-21-23-39(49-37)46(30-7-15-34(54-2)16-8-30)41-25-27-43(51-41)48(32-11-19-36(56-4)20-12-32)44-28-26-42(52-44)47(40-24-22-38(45)50-40)31-9-17-35(55-3)18-10-31/h5-28,49-50H,1-4H3/b45-37-,45-38-,46-39-,46-41-,47-40-,47-42-,48-43-,48-44-

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 109-97-7 pyrrole 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-87-0 4-methyl-benzaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 555-16-8 4-nitrobenzaldehdye 
• 111-25-1 1-bromo-hexane 
• 100-44-7 benzyl chloride 
• 106-94-5 propyl bromide 
• 106-95-6 allyl bromide 
• 176446-62-1 5-(4-methoxyphenyl)dipyrromethane 
• 71221-16-4 2,5-bis[1-(4-methoxyphenyl)-1-hydroxymethyl]thiophene 
• 159152-11-1 5-(4-bromophenyl)dipyrromethane 

Downstream Products

• 142230-21-5 N-(3-{5-[(1Z,4Z,9Z,15Z)-15-{3-[3-(Acetylamino-methyl)-adamantan-1-yl]-4-methoxy-phenyl}-10,20-bis-(4-methoxy-phenyl)-porphyrin-5-yl]-2-methoxy-phenyl}-adamantan-1-ylmethyl)-acetamide 
• 51094-17-8 5,10,15,20-tetrakis(4'-hydroxyphenyl)porphyrin 
• 50-00-0 formaldehyd 
• 34557-54-5 methane 
• 100-66-3 methoxybenzene 
• 71-43-2 benzene 
• 108-95-2 phenol 
• 130471-41-9 5-[1-{5-[1-{5-[Methoxy-[5-(4-methoxy-benzoyl)-1H-pyrrol-2-yl]-(4-methoxy-phenyl)-methyl]-1H-pyrrol-2-yl}-1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-5H-pyrrol-2-yl}-1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-1,5-dihydro-pyrrol-2-one 
• 142230-19-1 3-{2-Methoxy-5-[(5Z,10Z,14Z,19Z)-10,15,20-tris-(4-methoxy-phenyl)-porphyrin-5-yl]-phenyl}-adamantane-1-carboxylic acid 
• 142230-14-6 C-(3-{2-Methoxy-5-[(5Z,10Z,14Z,19Z)-10,15,20-tris-(4-methoxy-phenyl)-porphyrin-5-yl]-phenyl}-adamantan-1-yl)-methylamine 
• 142230-15-7 C-(3-{5-[(1Z,4Z,9Z,15Z)-15-[3-(3-Aminomethyl-adamantan-1-yl)-4-methoxy-phenyl]-10,20-bis-(4-methoxy-phenyl)-porphyrin-5-yl]-2-methoxy-phenyl}-adamantan-1-yl)-methylamine 
• 130471-42-0 (4Z,9Z)-1,15,21,24-tetrahydro-19-(4-methoxybenzoyl)-15-hydroxy-5,10,15-tris(4-methoxyphenyl)-23H-bilin-1-one 

Relevant academic research and scientific papers

Synthesis of sitting-atop type adducts of diphenyl and dimethyltin(IV) dihalides with meso-tetraarylporphyrins

Some molecular adducts of dimethyltin(IV) dichloride, diphenyltin(IV) dichloride and diphenyltin(IV) dibromide with para-substituted meso-tetraphenylporphyrin have been prepared. This adducts with general formula [(Me2SnCl2)2/s

Functionalization of silica surface by tetrahydroxyporphyrin via Si-olinkages

To construct an interface between a π-conjugated organic molecule and an inorganic/metal surface, 5,10,15,20-tetrakis[4-(5-hydroxypentyloxy)phenyl] porphyrin was chemisorbed on silica gel by refluxing in pyridine. Thermogravimetric analysis confirmed that

Convenient synthetic route of versatile 21-monothiatetraphenylporphyrins of the A4 and AB3 type

A novel convenient synthetic route for poly-functional 21- monothiatetraphenylporphyrins of the type A4 und AB3 having base labile substituents in meso position was developed. Using this method a series of symmetric and asymmetric 21-thiaporphyrins containing different functional groups at the meso position is reported. The new products were characterized by NMR, UV-Vis and mass spectroscopy.

Optimized synthesis of tetrakis(4-methoxyphenyl)porphin-Co(II)

Detailed kinetic investigation of Rothemund synthesis of porphyrins was conducted in different solvents. A one-pot synthesis of tetrakis(4- methoxyphenyl)porphin-Co(II) from pyrrole, anisic aldehyde, and cobalt acetate was developed that gave 35% isolated yield. Chlorobenzene was found to be the best solvent for the reaction. The synthesis can be done with either propionic or chloroacetic acid as catalyst with about the same yield. Cobalt prevents the synthesis of the porphyrin, so it has to be added in the reaction mixture only after the synthesis of the free porphyrin is finished. Optimum time is 2-2.5h at a temperature of 130C. Lower temperatures reduce the yield. Potentially, these dependencies can be applied to synthesis of other analogous porphyrins. Copyright Taylor & Francis Group, LLC.

Hydroxyalkyloxy substituted tetraphenylporphyrins: Mechanism and superoxide scavenging activity

The novel electrochemical approach based on coulometric response of electro-generated superoxide (O2?-) was used to determine scavenging properties of 2H-5,10,15,20-tetrakis (4-hydroxyphenyl)porphyrin (H2T(4-OHPh)P); 2H-5,

Expression of Fas antigen and apoptosis caused by 5,10,15,20-tetra(4-methoxyphenyl)porphyrin (TMP) on carcinoma cells: implication for photodynamic therapy

The photodynamic effects of 5,10,15,20-tetra(4-methoxyphenyl)porphyrin (TMP) on a Hep-2 cell line were investigated. TMP toxicity in the dark and in relation to illumination with visible light was examined. Hep-2 cells were treated with different TMP conc

Substituent and solvent effects on the hyperporphyrin spectra of diprotonated tetraphenylporphyrins

UV-visible spectra was studied for a series of p-substituted tetraphenylporphyrins (TPP) titrated with strong acid in various solvents. The longest wavelength absorption at 811 nm, however, was the greatest shift for any diprotonated substituted TPP. The magnitude of the shift was enhanced by a solvent effect. Diprotonated TAPP could be observed 10 fluoresce weakly in dichloromethane (DCM) solvent but not in dimethyl sulfoxide. DCM, which light exposure in the presence of a poryphyrin generated sufficient acid to significantly affect the spectrum. The effect was noted quantitatively by placing a dilute (4μM) TTP solution in a diode array spectrophotometer; an effective acid titration could be observed simply by exposing the sample to the monitoring beam over a period of 2 min.

Mono-oxido-bridged heterobimetallic and heterotrimetallic compounds containing titanium(IV) and chromium(III)

A series of oxido-bridged heterobi- and heterotrimetallic complexes, [(tmtaa)Ti=O→Cr(Por)Cl] and [(tmtaa)Ti=O→Cr(Por)←O=Ti(tmtaa)]+ (tmtaa = 7,16-dihydro-6,8,15,17-tetramethyldibenzo[b,i][1,4,8,11]tetraazacyclotetradecine; Por = 5,10,15,20-tetr

Photodynamic studies of metallo 5,10,15,20-tetrakis(4-methoxyphenyl) porphyrin: Photochemical characterization and biological consequences in a human carcinoma cell line

The photodynamic activities of the free-base 5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin (TMP) and their metal complexes with zinc(II) (ZnTMP), copper(II) (CuTMP) and cadmium(II) (CdTMP) have been compared in two systems: reverse micelle of n-heptane/so

Zinc(II) and copper(II) complexes of β-substituted hydroxylporphyrins as tumor photosensitizers

Novel photosensitizers β-(hydroquinon-2-yl)-5,10,15,20-tetra(4-hydroxylphenyl)porphyrinato zinc(II) (Zn(II)P) and β-(hydroquinon-2-yl)-5,10,15,20-tetra(4-hydroxylphenyl)porphyrinato copper(II) (Cu(II)P) were synthesized and characterized. Their ability of