221121-33-1

Basic information

• Product Name: 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone
• Synonyms: 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone
• CAS NO: 221121-33-1
• Molecular Weight: 222.194
• Mol File: 221121-33-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone(221121-33-1)
• EPA Substance Registry System: 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone(221121-33-1)

Safety Data

• Hazardous Substances Data: 221121-33-1(Hazardous Substances Data)

Upstream product

• 85068-28-6 2,6-difluorophenylacetic acid 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 221122-07-2 2-cyclohexylsulfanyl-6-(2,6-difluoro-benzyl)-3H-pyrimidin-4-one 
• 221122-06-1 2-cyclopentylthio-6-(2,6-difluorophenylmethyl)-3,4-dihydrogyrimidin-4-(3H)-one 
• 221122-03-8 2-butylsulfanyl-6-(2,6-difluoro-benzyl)-3H-pyrimidin-4-one 
• 221122-19-6 2-sec-butylsulfanyl-6-(2,6-difluoro-benzyl)-5-methyl-3H-pyrimidin-4-one 
• 221122-04-9 6-(2,6-difluoro-benzyl)-2-isobutylsulfanyl-3H-pyrimidin-4-one 
• 221122-05-0 2-sec-butylsulfanyl-6-(2,6-difluoro-benzyl)-3H-pyrimidin-4-one 
• 221122-02-7 6-(2,6-difluoro-benzyl)-2-isopropylsulfanyl-3H-pyrimidin-4-one 
• 221122-15-2 6-(2,6-difluorophenylmethyl)-3,4-dihydro-2-methylthio-5-methylpyrimidin-4(3H)-one 
• 221122-01-6 6-(2,6-difluorophenylmethyl)-3,4-dihydro-2-methylthiopyrimidin-4(3H)-one 
• 293300-24-0 6-(2,6-difluorophenylmethyl)-3,4-dihydro-5-ethyl-2-thioxopyrimidin-4(3H)-one 
• 221121-68-2 6-(2,6-difluorophenylmethyl)-3,4-dihydro-5-methyl-2-thioxopyrimidin-4(3H)-one 
• 221121-65-9 6-(2,6-difluorophenylmethyl)-3,4-dihydro-2-thioxopyrimidin-4(3H)-one 
• 872422-58-7 6-(2,6-difluoro-benzyl)-5-methyl-2-(4-nitro-benzylsulfanyl)-3H-pyrimidin-4-one 

Relevant articles and documents

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity

A simple and efficient methodology for the parallel solution-phase synthesis has been set up to obtain a series of thiouracils, in turn selectively S-benzylated under microwave irradiation to give new S-DABOs. Biological screening led to the identificatio

Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: Synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants

A series of novel S-DABO analogues, characterized by different substitution patterns at positions 2, 5, and 6 of the heterocyclic ring, were synthesized in a straightforward fashion by means of parallel synthesis and evaluated as inhibitors of human immun

5-alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin- 4(3H)-ones: Novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

Molecular modeling analysis of compounds belonging to the recently published series of dihydro-alkoxy-benzyl-oxopyrimidines (DABOs), such as S- DABOs and DATNOs, gave support to the design of new 2,6-disubstituted benzyl- DABO derivatives as highly potent