221122-15-2

Upstream product

• 221121-68-2 6-(2,6-difluorophenylmethyl)-3,4-dihydro-5-methyl-2-thioxopyrimidin-4(3H)-one 
• 74-88-4 methyl iodide 
• 221121-33-1 2-(2,6-difluoro-phenyl)-1-imidazol-1-yl-ethanone 
• 85068-28-6 2,6-difluorophenylacetic acid 
• 221121-48-8 ethyl 4-(2,6-difluorophenyl)-2-methyl-3-oxobutanoate 

Downstream Products

• 255898-25-0 6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5-methyl-2-methylthiopyrimidin-4(3H)-one 

Relevant academic research and scientific papers

Substituted 6-benzyl-4-oxopyrimidines, process for their preparation and pharmaceutical compositions containing them

The invention concerns novel substituted 6-benzyl-4-oxopyrimidines and pharmaceutically acceptable salts thereof. These compounds inhibit reverse transcriptase encoded by human immunodeficiency virus (HIV), and are useful to prevent and treat HIV infectio

5-alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin- 4(3H)-ones: Novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

Molecular modeling analysis of compounds belonging to the recently published series of dihydro-alkoxy-benzyl-oxopyrimidines (DABOs), such as S- DABOs and DATNOs, gave support to the design of new 2,6-disubstituted benzyl- DABO derivatives as highly potent