221123-52-0

Upstream product

• 221123-51-9 4-fluoro-3-nitrobenzyl iodide 
• 129150-61-4 3-(3-hydroxy-4-methoxyphenyl)-propionic acid methyl ester 
• 15017-52-4 4-(bromomethyl)-1-fluoro-2-nitrobenzene 
• 221123-49-5 3-(3-isopropyloxy-4-methoxyphenyl)propyl iodide 
• 221123-48-4 3-(3-isopropyloxy-4-methoxyphenyl)propanol-1 
• 221123-50-8 7-(3-isopropoxy-4-methoxyphenyl)-3-oxoheptanoic acid methyl ester 
• 197382-92-6 2-(4-fluoro-3-nitrobenzyl)-7-(3-isopropoxy-4-methoxyphenyl)-3-oxoheptanoic acid methyl ester 

Downstream Products

• 221123-61-1 5-[7-(4-fluoro-3-nitrophenyl)-5-hydroxyheptyl]-2-methoxyphenol 
• 197382-99-3 aceroside IV perbenzoate 

Relevant academic research and scientific papers

Asymmetric Synthesis of (-)-Pterocarine and (-)-Galeon via Chiral Phase Transfer-Catalyzed Atropselective Formation of Diarylether Cyclophane Skeleton

Pterocarine and galeon are typical examples of diarylether heptanoids (DAEHs) with planar chirality due to the strictly constrained conformations in their molecular skeletons. The characterized oxa[1,7]metapara-cyclophane motifs in DAEHs impose great challenges for their enantioselective synthesis. The asymmetric syntheses of (-)-pterocarine and (-)-galeon are demonstrated by employing a chiral phase transfer-catalyzed highly enantioselective SNAr cyclization as the key step for the formation of a diarylether cyclophane skeleton.

A unified strategy toward the synthesis of acerogenin-type macrocycles: Total syntheses of acerogenins A, B, C, and L and aceroside IV

A general strategy for the synthesis of acerogenin-type diarylheptanoids containing an endocyclic biaryl ether bond has been developed, and convergent total syntheses of acerogenin A, B, C, and L and aceroside IV have been accomplished. Cycloetherificatio