22116-72-9

Basic information

• Product Name: N-(4-chlorophenyl)-N-[4-(methylsulfanyl)benzylidene]amine
• Synonyms: N-(4-chlorophenyl)-N-[4-(methylsulfanyl)benzylidene]amine
• CAS NO: 22116-72-9
• Molecular Formula: C₁₄H₁₂ClNS
• Molecular Weight: 261.76978
• Mol File: 22116-72-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-chlorophenyl)-N-[4-(methylsulfanyl)benzylidene]amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-N-[4-(methylsulfanyl)benzylidene]amine(22116-72-9)
• EPA Substance Registry System: N-(4-chlorophenyl)-N-[4-(methylsulfanyl)benzylidene]amine(22116-72-9)

Safety Data

• Hazardous Substances Data: 22116-72-9(Hazardous Substances Data)

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 1239357-83-5 C₁₆H₁₃ClN₂S 
• 1239645-73-8 4‐chloro‐N‐(4‐(methylsulfonyl)benzylidene)aniline 
• 385777-23-1 3-(4-chlorophenyl)-2-(4-(methylthio)phenyl)-1,3-benzdiazinan-4-one 

Relevant articles and documents

Synthesis and photophysical properties of fluorescent arylstyrylimidazo[1,2-a]pyridine-based donor-acceptor chromophores

A series of novel fluorescent arylstyrylimidazo[1,2-a]pyridines was synthesized and fully characterized. All styryl derivatives have an E-configuration of the vinyl double bond as unequivocally shown by 1H NMR spectroscopy. It was observed that

Iron-catalyzed synthesis of secondary amines: On the way to green reductive aminations

Amines represent important intermediates in chemical and biological processes. Herein, we describe the use of a nanostructured iron-based catalyst for the tandem reductive amination between nitroarenes and aldehydes using hydrogen as reductant. The nanostructured iron-catalyst is prepared by immobilization of an iron-phenanthroline complex onto a commercially available carbon support. In the reaction sequence a primary amine is formed in situ from the corresponding nitro compound. Reversible condensation with aldehydes forms the respective imines, which are finally reduced to the desired secondary amine. This synthesis of secondary amines is atom-economical and environmentally attractive using cheap and readily available organic compounds as starting materials.

1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells

A series of 1,5-diarylimidazoles with 4-methylsulfonylphenyl group were prepared and evaluated for the inhibitory activities against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells. Most of synthesized 1,5-diarylimidazoles exhibited strong inhibitory activities regardless of the position of the 4-methylsulfonylphenyl group. The 1,5-diarylimidazoles with a halogen atom (3c-3h, 3n-3p) gave mostly excellent inhibitory activities regardless of the position and species of the halogen atom. Whereas the 1,5-diarylimidazoles with two fluorine atoms (3k, 3l, 3r, 3s) showed rather reduced inhibitory activities.