221187-59-3

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 1026378-85-7 (2S)-3-benzyloxy-2-hydroxypropyl trifluoromethanesulfonate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 16495-03-7 (S)-4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 221187-63-9 (2S,3R,5R)-5-Benzyloxymethyl-2-pentyl-tetrahydro-furan-3-ol 
• 221187-58-2 (2S,5R)-5-Benzyloxymethyl-2-pentyl-dihydro-furan-3-one 

Relevant academic research and scientific papers

Facile Route to 3,5-Disubstituted Morpholines: Enantioselective Synthesis of O-Protected trans-3,5-Bis(hydroxymethyl)morpholines

(Equation presented) trans-3,5-Bis(benzyl/terf-butyldiphenylsilyloxymethyl) morpholines, promising candidates for the C2-symmetric class of chiral reagents, were prepared with excellent optical purity. A key step in the synthesis is the couplin

Synthesis of (6S,7S,9R,10R)-6,9-epoxynonadec-18-ene-7,10-diol, a marine epoxy lipid isolated from the brown alga, Notheia anomala, by an oxiranyl anion strategy

The stereocontrolled synthesis of (6S,7S,9R,10R)-6,9-epoxynonadec-18- ene-7,10-diol, isolated from the brown alga, Notheia anomala, has been achieved. The key 2,3,5-trisubstituted tetrahydrofuran ring was constructed by alkylation of the sulfonyl-stabilized oxiranly anion followed by 5-endo cyclization.