221202-14-8

Basic information

• Product Name: 2-(Difluoromethoxy)-6-fluoro-benzonitrile
• Synonyms: 2-(Difluoromethoxy)-6-fluoro-benzonitrile
• CAS NO: 221202-14-8
• Molecular Formula: C₈H₄F₃NO
• Molecular Weight: 187.1186696
• Mol File: 221202-14-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(Difluoromethoxy)-6-fluoro-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Difluoromethoxy)-6-fluoro-benzonitrile(221202-14-8)
• EPA Substance Registry System: 2-(Difluoromethoxy)-6-fluoro-benzonitrile(221202-14-8)

Safety Data

• Hazardous Substances Data: 221202-14-8(Hazardous Substances Data)

Usage

Description

2-(Difluoromethoxy)-6-fluoro-benzonitrile is a synthetic chemical compound that belongs to the class of organic compounds known as fluoroarenes. It is characterized by the presence of fluorine and nitrogen atoms, and is known for its colorless appearance and solid state at room temperature.

Uses

Used in Chemical Research and Synthesis:
2-(Difluoromethoxy)-6-fluoro-benzonitrile is used as a chemical intermediate for the synthesis of various complex organic molecules. Its unique structure, which includes fluorine and nitrogen atoms, makes it a valuable component in the development of new chemical entities.
Used in Pharmaceutical Industry:
2-(Difluoromethoxy)-6-fluoro-benzonitrile is used as a building block in the design and synthesis of potential drug candidates. Its incorporation into molecular structures can impart specific properties, such as increased lipophilicity or altered metabolic stability, which may be beneficial for drug development.
Used in Material Science:
2-(Difluoromethoxy)-6-fluoro-benzonitrile is used as a component in the development of new materials with tailored properties. Its fluorinated nature can contribute to the creation of materials with improved thermal stability, chemical resistance, or other desirable characteristics.

Upstream product

• 75-45-6 Chlorodifluoromethane 
• 140675-43-0 2-Fluoro-6-hydroxybenzonitrile 

Downstream Products

• 1153055-77-6 [2-(difluoromethoxy)-6-fluorophenyl]-methanamine 
• 889097-53-4 2-difluoromethoxy-6-propylsulfanylbenzonitrile 

Relevant articles and documents

A SUBSTITUTED BENZIMIDAZOLE DERIVATIVE AS A MODULATOR OF TNF ACTIVITY

2-(5-{1-[2-(Difluoromethoxy)-6-fluorobenzyl]-2-methyl-1H-benzimidazol-6- yl}pyrimidin-2-yl)propan-2-ol, or a pharmaceutically acceptable salt thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS

The invention relates to 2-cyano-3-(halo)alkoxy-benzenesulfonamide compounds (I), where the variables Alk and R1 to R5 are as defined in claim 1, and/or to their agriculturally useful salts. Moreover, the present invention relates to: the use of compounds (I) and/or their salts for combating animal pests; agricultural compositions comprising such an amount of at least one compound of the general formula (I) and/or at least one agriculturally useful salt of (I) and at least one inert liquid and/or solid agronomically acceptable carrier that it has a pesticidal action and, if desired, at least one surfactant; and a method of combating animal pests which comprises contacting the animal pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation with a pesticidally effective amount of at least one2-cyano-3-(halo)alkoxy-benzenesulfonamide compound of the formula (I) and/or at least one agriculturally acceptable salt thereof; a method for the for the protection of seeds from soil insects and of the resulting plant's roots and shoots from soil and foliar insects comprising contacting the seeds before sowing and/or after pregermination with a 2-cyano-3-(halo)alkoxy-benzenesulfonamide compound of the general formula (I).