75-45-6 Usage
Chemical Properties
Chlorodifluoromethane is a nonflammable,
colorless, nearly odorless gas.
Uses
Different sources of media describe the Uses of 75-45-6 differently. You can refer to the following data:
1. Refrigerant, low-temperature solvent, fluorocarbon resins, especially tetrafluoroethylene polymers.
2. Aerosol propellant; refrigerant; lowtemperature
solvent
General Description
Difluorochloromethane is a colorless gas with an ethereal odor. Difluorochloromethane is shipped as a liquefied gas under its own vapor pressure. Difluorochloromethane is noncombustible. Difluorochloromethane can asphyxiate by the displacement of air. Contact with the liquid can cause frostbite. Toxic gases can be produced in fires involving Difluorochloromethane. Exposure of the container to prolonged heat or fire may cause Difluorochloromethane to rupture violently and rocket.
Reactivity Profile
Difluorochloromethane is incompatible with the following: Alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc) .
Hazard
Asphyxiant. Central nervous system
impairment, cardiac sensitization. Questionable
carcinogen.
Health Hazard
Inhalation at greater than 10% concentration in air may cause narcosis. Liquid may cause frostbite.
Fire Hazard
Special Hazards of Combustion Products: Decomposition gases are toxic and irritating.
Safety Profile
Mddly toxic by
inhalation. Experimental reproductive
effects. Mutation data reported. An
asphpant in hgh concentrations. At
elevated pressures, 50% mixtures with air
are combustible although ignition is dfficult.
When heated to decomposition it emits
toxic fumes of Fand Cl-. See also
CHLORINATED HYDROCARBONS,
ALIPHATIC; and FLUORIDES.
Potential Exposure
Chlorodifluoromethane is used as an
aerosol propellant, refrigerant, and low-temperature solvent.
It is used in the synthesis of polytetrafluoroethylene
(PTFE).
Carcinogenicity
In one study, an oral dose of
300mg of HCFC 22/kg of body weight was given to
36 male and 36 female rats 5 days/week for 52 weeks.
The rats were held for 125 weeks compared to controls.
There was no evidence of any treatment related increase in
tumors. In an inhalation study 60 male and
60 female rats were exposed by inhalation to levels of
5000 ppm of HCFC 22. The exposures were 4 h/day,
5 days/week for 104 weeks (rats) or 78 weeks (mice).
Shipping
UN1018 Chlorodifluoromethane, Hazard Class:
2.2; Labels: 2.2-Non-flammable compressed gas. Cylinders
must be transported in a secure upright position, in a wellventilated truck. Protect cylinder and labels from physical
damage. The owner of the compressed gas cylinder is the
only entity allowed by federal law (49CFR) to transport
and refill them. It is a violation of transportation regulations to refill compressed gas cylinders without the express
written permission of the owner.
Incompatibilities
The liquefied gas poured into water can
be violently explosive. This is due to the phase transition
from superheated liquid to vapor. Chlorodifluoromethane reacts violently with alkalies and alkaline earth
metals; powdered aluminum; sodium, potassium, and zinc;
causing fire and explosion hazard. Moisture and rust cause
slow decomposition, forming toxic gases. Attacks some
plastics, rubber, and coatings. Decomposes in heat forming
fumes of chlorine, hydrogen chloride, HF, and phosgene.
Attacks magnesium and its alloys.
Waste Disposal
Return refillable compressed
gas cylinders to supplier. Return to vendor or send to
licensed waste disposal company.
Check Digit Verification of cas no
The CAS Registry Mumber 75-45-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 75-45:
(4*7)+(3*5)+(2*4)+(1*5)=56
56 % 10 = 6
So 75-45-6 is a valid CAS Registry Number.
InChI:InChI=1/CHClF2/c2-1(3)4/h1H
75-45-6Relevant articles and documents
Nagase et al.
, p. 684 (1967)
Edwards, J. W.,Small, P. A.
, p. 1329 - 1329 (1964)
2-Chloro-2,2-difluoracetamide (ClF2CC(O)NH2). Thermal decomposition, vapour infrared, mass spectrometry, low-temperature NMR, and theoretical studies. Solvent effects on conformational preferences
Iriarte, Ana G.,Cutin, Edgardo H.,Auergello, Gustavo A.
, p. 1366 - 1372 (2011)
Gas-phase thermal decomposition of 2-chloro-2,2-difluoracetamide (CDFA) was studied at temperatures between 270 and 290°C. The rate constant for the decomposition follows the Arrhenius equation. k = (5.5 ± 0.3) · 1016s-1 exp [-(104±4)kj mol-1/RT] Mass spectrometry was used to analyze the decomposition pattern of the title compound. The FT-IR spectrum of the vapour phase and the infrared spectra of CDFA in protic and aprotic solvents were recorded. Potential energy surfaces were studied by theoretical calculations performed at the density functional theory level (PBEPBE and B3LYP methods) using the 6-31G*, 6-31+G*, 6-311+G**, aug-cc-pVDZ, and aug-cc-pVTZ basis sets. CSIRO 2011.
Selective reduction of a C–Cl bond in halomethanes with Et3GeH at nanoscopic Lewis acidic Aluminium fluoride
Mei?ner, Gisa,Feist, Michael,Braun, Thomas,Kemnitz, Erhard
, p. 234 - 241 (2017/09/12)
The selective activation of C–Cl bonds of hydrochlorofluoromethanes and chloromethanes at moderate reaction conditions using ACF in a combination with Et3GeH is presented. The reactions of the chloromethanes (CH3Cl, CH2Cl2, CHCl3 and CCl4) in the presence of Et3GeH and ACF as catalyst led to the activation of only one C–Cl bond resulting in the hydrodechlorination. Friedel-Crafts reactions with benzene as solvent are suppressed by Et3GeH. A selective hydrodechlorination of hydrochlorofluoromethanes was achieved, because a transformation of a C–F bond into a C–H bond by the combination of ACF with Et3GeH did not occur. Supporting PulseTA experiments illustrated the interaction between the solid catalyst and Et3GeH, the solvent benzene or CH2Cl2.
A combination of three fluoromethane cracking process for preparing
-
Paragraph 0025; 0026; 0030, (2017/02/24)
The invention provides a technique for preparing monochlorodifluoromethane by decomposing trifluoromethane. The technique comprises the steps of: feeding the raw materials trifluoromethane and methane chloride into a reactor filled with a catalyst in the mol ratio of 0.1-10, and carrying out a decomposition reaction at a temperature ranging from 150 to 350 DEG C for 3-30 seconds to obtain a mixture of trifluoromethane, methane chloride, dichloromonofluoromethane and monochlorodifluoromethane; obtaining monochlorodifluoromethane directly through separation, reacting dichloromonofluoromethane separated out with hydrogen fluoride to produce monochlorodifluoromethane, and separating out and recovering trifluoromethane and methane chloride in the mixture as the reaction mixture continuously. The method has the advantage that the harm on the environment caused by trifluoromethane emission is greatly avoided.
