221253-04-9Relevant academic research and scientific papers
Asymmetric allylic alkylation of ketone enolates: An asymmetric claisen surrogate
Burger, Erin C.,Tunge, Jon A.
, p. 4113 - 4115 (2007/10/03)
(Chemical Equation Presented) The combination of catalytic palladium(0) and Trost ligand provides an effective catalyst for the rearrangement of allyl β-ketoesters. The mechanism of the transformation involves formation of π-allyl palladium intermediates which undergo enantioselective attack by ketone enolates. Decarboxylation of β-ketocarboxylates allows regiospecific generation of enolates under extremely mild conditions.
Ring opening of cyclopropane in tricyclo[4.3.0.02,9]nonan-3-one with electrophile-nucleophile reagents
Fernandez-Mateos, A.,Alonso, J. J. Perez,Gonzales, R. Rubio
, p. 847 - 860 (2007/10/03)
Four tricyclo[4.3.0.02,9]nonan-3-one systems were treated with TBDMSI, TMSTFA and TMSTFA/NaSPh, affording different cyclopropane cleavage products, depending on the location of the substituent and the nature of the reagent.
