5395-20-0

Basic information

• Product Name: BENZYLP-TOLYLSULFONE
• Synonyms: BENZYLP-TOLYLSULFONE
• CAS NO: 5395-20-0
• Molecular Formula: C₁₄H₁₄O₂S
• Molecular Weight: 246.32476
• Mol File: 5395-20-0.mol
• Article Data: 100

Chemical Properties

• Boiling Point: 429.3°Cat760mmHg
• Flash Point: 264.5°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 3.56E-07mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: BENZYLP-TOLYLSULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYLP-TOLYLSULFONE(5395-20-0)
• EPA Substance Registry System: BENZYLP-TOLYLSULFONE(5395-20-0)

Safety Data

• Hazardous Substances Data: 5395-20-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H14O2S/c1-12-7-9-14(10-8-12)17(15,16)11-13-5-3-2-4-6-13/h2-10H,11H2,1H3

Upstream product

• 68342-73-4 phenyl-(toluene-4-sulfonyl)-acetic acid 
• 100-44-7 benzyl chloride 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 100-39-0 benzyl bromide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 6996-92-5 benzeneseleninic acid 
• 18440-49-8 N-benzyl-N-p-toluenesulfonylhydrazine 
• 1950-78-3 p-toluenesulfonyl iodide 
• 98-59-9 p-toluenesulfonyl chloride 
• 5023-60-9 1-benzylsulfanyl-4-methyl-benzene 
• 200055-89-6 4-(4-toluenesulfonyloxy)coumarin 
• 31913-41-4 6-methyl-4-tosyloxy-2(2H)-pyranone 
• 4525-46-6 benzyltrimethylammonium iodide 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 

Downstream Products

• 26958-46-3 1-(2,2-Bis-methylsulfanyl-1-phenyl-ethenesulfonyl)-4-methyl-benzene 
• 101-81-5 Diphenylmethane 
• 71376-50-6 1-Methyl-4-(1-phenyl-pentane-1-sulfonyl)-benzene 
• 71376-49-3 1-methyl-4-(1-phenylpropylsulfonyl)benzene 
• 219702-92-8 3-Cyclohexylidene-1-phenyl-1-(toluene-4-sulfonyl)-propan-2-one 
• 17608-67-2 cis-2,3-diphenyl-1-benzoylcyclopropane 
• 1136166-67-0 tert-butyl p-[p-tolylsulfonyl(phenyl)methyl]benzoate 
• 1136166-64-7 phenyl(m-trifluoromethylphenyl)methyl p-tolyl sulfone 
• 113181-46-7 1-methyl-4-((phenyl(p-tolyl)methyl)sulfonyl)benzene 
• 1136166-73-8 phenyl(m-tolyl)methyl p-tolyl sulfone 
• 102078-57-9 p-chlorophenyl(phenyl)methyl p-tolyl sulfone 
• 113181-45-6 phenyl(o-tolyl)methyl p-tolyl sulfone 
• 5433-78-3 diphenylmethyl p-tolyl sulfone 
• 65240-52-0 (4-methylbenzenesulfonyl)(phenyl)methanone 

Relevant articles and documents

Cobalt-Catalyzed Redox-Neutral Sulfonylative Coupling from (Hetero)aryl Boronic Acids, Ammonium Salts and Potassium Metabisulfite

An efficient cobalt-catalyzed redox-neutral sulfonylative coupling to afford (hetero)aryl alkyl sulfones from boronic acids, ammonium salts and potassium metabisulfite has been realized. Commercially available and air-stable CoCl2, in combination with phenanthroline ligand, is sufficient to achieve rapid and high-yielding conversion of the reactants into the corresponding sulfones. This practical transformation proceeds smoothly through C?N bond cleavage under redox-neutral catalytic conditions and shows broad functional-group tolerance. Other carbon based electrophiles, including diaryliodonium salts, heteroaryl halides, and carbonates were compatible. Further transformation of aryl alkyl sulfones then allows conversion into olefins, alkenyl sulfones and halogenated sulfones, respectively, in a one-pot process.

Vanadium-catalyzed Selective Oxidation of Sulfides to Sulfoxides and Sulfones with H2O2

Abstract: A direct selective approach to the oxidation of sulfides to sulfoxides andsulfones with H2O2 in moderate togood yields is developed. The reaction proceeds in the presence of 2 mol % ofVO(acac)2 at room temperature. All sulfoxides andsulfones were detected by gas chromatography, and the molecular structures of2-methylbenzyl 4-methylphenyl sulfone, 4-methylbenzyl 4-methylphenyl sulfone,2-bromobenzyl 4-methylphenyl sulfone, and 4-tert-butylbenzyl benzyl sulfone were determined by singlecrystal X-ray crystallography.

Synthesis of sulfone derivatives via palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides

A palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides for the synthesis of various benzyl sulfones is reported. This novel protocol shows widespread functional group tolerance, leading to the desired sulfones in moderate to excellent yields.