22126-97-2Relevant academic research and scientific papers
Novel quinazolinone derivatives as 5-HT7 receptor ligands
Na, Yong Ho,Hong, Sung Ho,Lee, Jung Hyang,Park, Woo-Kyu,Baek, Du-Jong,Koh, Hun Yeong,Cho, Yong Seo,Choo, Hyunah,Pae, Ae Nim
, p. 2570 - 2578 (2008/09/21)
5-HT7 receptor antagonists generated antidepressant-like effects in animal model and the involvement of the 5-HT7 receptor in other pathophysiological mechanisms such as thermoregulation, learning and memory, and sleep has been highl
METHOD OF PREPARING 3-PHENYL-2-[9H-PURIN-6-YLAMINO)-METHYL]-3H-QUINAZOLIN-4-ONE AND SUBSTITUTED AND RELATED COMPOUNDS
-
Page/Page column 10; 21, (2010/02/14)
A method of synthesizing compounds of structural formulae (II), (IIa), and (III), in high yield and high stereospecific selectivity is disclosed. (IIa, R5≠H, S-enantiomer)
Electroreduction of Some Potential Antimicrobial Thiosemicarbazide Derivatives of Quinazolin-4(3H)-one
Ismail, Mohamed I.
, p. 585 - 590 (2007/10/02)
Polarographic data for a series of 3-phenyl-2-substituted thiocarbamoylhydrazonomethylquinazolin-4(3H)-ones (with antimicrobial activity), in 50percent ethanolic aqueous buffers covering a wide range of pH are reported and discussed.A mechanism interpreting the electrode process, in both acidic and alkaline media, is proposed and confirmed via the identification of CPE products, Hammett's ?-E1/2 relation and pKa determination.
Quinazolinones, 2. Syntheses and Some Reactions of 2-Azido-methyl-3-aryl-4-quinazolinones
Domanig, Rainer
, p. 1195 - 1202 (2007/10/02)
Starting with the chloromethyl compounds 7 the new 2-azidomethyl-3-aryl-4-quinazolinones 8a-h were prepared, some of which have been reduced so far to the corresponding amines 9a, b, e, g by H2S in good yield.As a first example for the capability of the a
