131532-69-9

Upstream product

• 79-19-6 thiosemicarbazide 
• 20873-11-4 (3-phenyl-4(3H)-quinazolinon-2-yl)carboxaldehyde 
• 4346-94-5 thiosemicarbazide hydrochloride 
• 2385-23-1 2-Methyl-3-phenyl-4(3H)-quinazolinone 

Downstream Products

• 169471-07-2 <2-(3-phenyl-4(3H)-quinazolinon-2-yl)-4-oxo-2-thiazolidinylidene>-hydrazone 
• 169471-08-3 3-<(3-phenyl-4(3H)-quinazolinon-2-yl)-methylene>amino-2-thioxo-4-imidazolidinone 
• 17356-08-0 thiourea 
• 22126-97-2 2-Aminomethyl-3,4-dihydro-3-phenyl-4-chinazolinon 

Relevant academic research and scientific papers

Synthesis and antiinflammatory properties of some novel thiazolidinones and imidazolidinones derived from 4-(3-phenyl-4(3H)-quinazolinon-2-yl)-3-thiosemicarbazone

A series of quinazolinone thiazolidinone and imidazolidinone derivatives were prepared. These compounds were evaluated for their antiinflammatory activity. The most active compounds (6b, 6c and 6d) were found to be superior to phenylbutazone as they were devoid of any ulcerogenic activity.

Electroreduction of Some Potential Antimicrobial Thiosemicarbazide Derivatives of Quinazolin-4(3H)-one

Polarographic data for a series of 3-phenyl-2-substituted thiocarbamoylhydrazonomethylquinazolin-4(3H)-ones (with antimicrobial activity), in 50percent ethanolic aqueous buffers covering a wide range of pH are reported and discussed.A mechanism interpreting the electrode process, in both acidic and alkaline media, is proposed and confirmed via the identification of CPE products, Hammett's ?-E1/2 relation and pKa determination.