221290-74-0

Upstream product

• 380414-34-6 (E)-4-[(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl]-2-methyl-but-2-enoic acid 
• 380414-33-5 (Z)-4-[(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl]-2-methyl-but-2-enoic acid 
• 221290-58-0 (Z)-4-[(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl]-2-methyl-but-2-en-1-ol 
• 221290-56-8 [(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl]-acetic acid 
• 380414-42-6 2-((1R,5R,6R)-6-Dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl)-ethanol 
• 221290-71-7 acetic acid (1S,4R,5R)-4-dimethoxymethyl-5-isopropyl-2-methylcyclohex-2-enyl ester 
• 221290-57-9 [(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enyl]-acetaldehyde 
• 221290-55-7 (1S,4R,5R)-4-dimethoxymethyl-5-isopropyl-2-methylcyclohex-2-enol 
• 221290-54-6 (4R,5R)-4-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enone 
• 221290-61-5 {(2S,3R)-3-[(1R,5R,6R)-6-dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enylmethyl]-2-methyl-oxiranyl}-methanol 

Relevant academic research and scientific papers

Synthetic studies on the sarcodictyins: Synthesis of fully functionalized cyclization precursors

A strategy featuring a key retrosynthetic disconnection at the C2-C3 position was applied to the total synthesis of the common diterpenoid tricyclic skeleton of sarcodictyins and eleutherobin. Fully functionalized cyclization precursors were accessed via a brief and convergent route, making use of unprecedented synthetic transformations.