2213-82-3

Basic information

• Product Name: 2,5-dichloro-1,3-dinitrobenzene
• Synonyms: 2,5-dichloro-1,3-dinitrobenzene
• CAS NO: 2213-82-3
• Molecular Formula: C₆H₂Cl₂N₂O₄
• Molecular Weight: 236.99708
• EINECS: 218-673-6
• Mol File: 2213-82-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 105 °C
• Boiling Point: 315.8°Cat760mmHg
• Flash Point: 144.8°C
• Appearance: /
• Density: 1.729g/cm³
• Vapor Pressure: 0.000793mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 2,5-dichloro-1,3-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dichloro-1,3-dinitrobenzene(2213-82-3)
• EPA Substance Registry System: 2,5-dichloro-1,3-dinitrobenzene(2213-82-3)

Safety Data

• Hazardous Substances Data: 2213-82-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 267, 1979 DOI: 10.1021/jo01316a024

InChI:InChI=1/C6H2Cl2N2O4/c7-3-1-4(9(11)12)6(8)5(2-3)10(13)14/h1-2H

Upstream product

• 89-61-2 2,5-dichloronitrobenzene 
• 71-43-2 benzene 
• 106-48-9 4-chloro-phenol 
• 106-46-7 para-dichlorobenzene 
• 606-21-3 1-chloro-2,6-dinitrobenzene 
• 618-86-0 1-chloro-3,5-dinitrobenzene 
• 99-65-0 meta-dinitrobenzene 
• 88-87-9 4-chloro-2,6-dinitrophenol 
• 98-59-9 p-toluenesulfonyl chloride 
• 5388-62-5 4-chloro-2,6-dinitroaniline 

Downstream Products

• 39522-55-9 1-Nitro-3-chlorphenoxazin 
• 99514-36-0 6-chloro-4-nitro-2-p-tolyl-2H-benzotriazole 
• 99513-83-4 6-chloro-4-nitro-2-p-tolyl-2H-benzotriazole-1-oxide 
• 56205-36-8 3-(4-chloro-2,6-dinitro-phenyl)-2-thioxo-thiazolidin-4-one 
• 68142-47-2 5-benzylidene-3-(4-chloro-2,6-dinitro-phenyl)-2-thioxo-thiazolidin-4-one 
• 83547-70-0 1-(2-hydroxyethoxy)-2,6-dinitro-4-chlorobenzene 
• 93352-75-1 4-Chlor-2,6-dinitro-2'-amino-4'-methyl-diphenylamin 
• 51676-59-6 O-Methylxanthogensaeure-4-chlor-2,6-dinitrophenylester 
• 51676-69-8 O-Ethylxanthogensaeure-4-chlor-2,6-dinitrophenylester 
• 2431-13-2 diethyl-dithiocarbamic acid-(4-chloro-2,6-dinitro-phenyl ester) 
• 3379-61-1 p-Chlorophenyl-4-chloro-2,6-dinitrophenyl-sulfid 
• 88-87-9 4-chloro-2,6-dinitrophenol 
• 5388-62-5 4-chloro-2,6-dinitroaniline 
• 37138-82-2 2-methoxy-3,5-dichloronitrobenzene 

Relevant articles and documents

Synthesis of 6-aminobenzopentathiepines by reactions of 4-nitrobenzodithiol-2-ones with NaHS

The reactions of benzodithiol-2-ones containing a 4-nitro group with NaHS led to mixtures of 6- aminobenzopentathiepines and 4-nitrobenzotrithiols. The product ratio and yields depend on the substituent in the aromatic ring. Based on the yields of benzopentathiepines, the following series of substituent efficiency can be inferred: CF3 ? F, Cl > CN. Aminobenzopentathiepines are probably formed via the intermediate benzotrithiols; the transformation apparently starts with the reduction of the nitro group.

Metabolism and disposition of 1,4,7,8-tetrachlorodibenzo-p-dioxin in rats

Metabolism studies of 1,4,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a relatively nontoxic dioxin congener, were undertaken to gain a better understanding of mammalian metabolism of dioxins without the problems associated with the use of the most toxic congener, 2,3,7,8-TCDD. 14C- 1,4,7,8-TCDD was dosed to conventional and bile-cannulated rats at a level of 8 mg/kg. The 14C was excreted almost entirely in 72 hours with the major routes of excretion feces and bile. Metabolites were identified from the feces, bile, and urine by GC-MS or negative ion FAB MS and 1H NMR. The two major fetal metabolites were hydroxylated tetra- and triCDDs. Glucuronide and sulfate conjugates of these hydroxyl metabolites were found in the urine and bile. Minor metabolites included dichlorocatechol, dihydroxylated tetra- and triCDDs, and conjugates of these compounds.

Electrophilic Aromatic Substitution. Part 34. Nitration of 1-Chloro-4-nitrobenzene, 1,3-Dichloro-2-nitrobenzene, 1,3-Dinitrobenzene, 1-Chloro-2,4-dinitrobenzene, and 2-Chloro-1,3-dinitrobenzene in Sulphuric Acid and Oleum

Yields of the expected nitro products from 1-chloro-4-nitrobenzene and 1,3-dichloro-2-nitrobenzene nitrated at 25 deg C in sulphuric acid or oleum containing 1 mol dm-3 nitric acid were quantitative.The rate profile for nitration of 1,3-dichloro-2-nitrobenzene is normal, but sulphonation is a competing process when the concentration of nitric acid is low.Kinetics of nitration of 1,3-dinitrobenzene at 150 deg C are reported; yields of 1,3,5-trinitrobenzene, the only detected aromatic product, are low.The title chlorodinitrobenzenes each give, on nitration at 130 deg C, a dichlorodinitrobenzene as well as a chlorotrinitrobenzene.The kinetics and yields of the two products from 1-chloro-2,4-dinitrobenzene under a variety of conditions are reported and discussed in relation to a previously proposed mechanism.