221302-48-3

Upstream product

• 198417-69-5 tert-butyl [(1R)-2-(tert-butyldiphenylsilyloxy)-1-(hydroxymethyl)-ethyl]carbamate 
• 154456-41-4 [(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-formyl-ethyl]-carbamic acid tert-butyl ester 
• 1730-25-2 allylmagnesium bromide 

Downstream Products

• 221302-49-4 5-allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 221302-52-9 4-(tert-butyl-diphenyl-silanyloxymethyl)-5-(3-ethoxycarbonyl-2-oxo-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 221302-51-8 4-(tert-butyl-diphenyl-silanyloxymethyl)-5-(3-ethoxycarbonyl-2-hydroxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 221302-54-1 6-tert-butoxycarbonylamino-7-(tert-butyl-diphenyl-silanyloxy)-3,5-dihydroxy-heptanoic acid ethyl ester 
• 221302-53-0 6-tert-butoxycarbonylamino-7-(tert-butyl-diphenyl-silanyloxy)-5-hydroxy-3-oxo-heptanoic acid ethyl ester 
• 221302-50-7 4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-5-(2-oxo-ethyl)-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of N-boc-galantinic acid ethyl ester

An efficient synthesis of the biologically important title amino acid is described. The key features of the synthesis are, i) a chelation controlled Grignard reaction towards stereoselective formation of the syn-1,2-amino alcohol unit, and ii) construction of the anti-1,3-diol moiety via hydroxy group directed stereoselective reduction of a proximal ketone.