221302-49-4

Basic information

• Product Name: 5-allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• CAS NO: 221302-49-4
• Molecular Weight: 509.761
• Mol File: 221302-49-4.mol

Chemical Properties

• CAS DataBase Reference: 5-allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(221302-49-4)
• EPA Substance Registry System: 5-allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(221302-49-4)

Safety Data

• Hazardous Substances Data: 221302-49-4(Hazardous Substances Data)

Upstream product

• 77-76-9 2,2-dimethoxy-propane 
• 221302-48-3 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester 
• 154456-41-4 [(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-formyl-ethyl]-carbamic acid tert-butyl ester 
• 198417-69-5 tert-butyl [(1R)-2-(tert-butyldiphenylsilyloxy)-1-(hydroxymethyl)-ethyl]carbamate 

Downstream Products

• 221302-53-0 6-tert-butoxycarbonylamino-7-(tert-butyl-diphenyl-silanyloxy)-5-hydroxy-3-oxo-heptanoic acid ethyl ester 
• 221302-54-1 6-tert-butoxycarbonylamino-7-(tert-butyl-diphenyl-silanyloxy)-3,5-dihydroxy-heptanoic acid ethyl ester 
• 221302-51-8 4-(tert-butyl-diphenyl-silanyloxymethyl)-5-(3-ethoxycarbonyl-2-hydroxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 221302-52-9 4-(tert-butyl-diphenyl-silanyloxymethyl)-5-(3-ethoxycarbonyl-2-oxo-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 221302-50-7 4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-5-(2-oxo-ethyl)-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Stereoselective synthesis of N-boc-galantinic acid ethyl ester

An efficient synthesis of the biologically important title amino acid is described. The key features of the synthesis are, i) a chelation controlled Grignard reaction towards stereoselective formation of the syn-1,2-amino alcohol unit, and ii) construction of the anti-1,3-diol moiety via hydroxy group directed stereoselective reduction of a proximal ketone.