221358-52-7

Basic information

• Product Name: Methanone, [(2R,3S)-3-(3-chlorophenyl)oxiranyl]phenyl-
• CAS NO: 221358-52-7
• Molecular Formula: C15H11ClO2
• Molecular Weight: 258.704
• Mol File: 221358-52-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Methanone, [(2R,3S)-3-(3-chlorophenyl)oxiranyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [(2R,3S)-3-(3-chlorophenyl)oxiranyl]phenyl-(221358-52-7)
• EPA Substance Registry System: Methanone, [(2R,3S)-3-(3-chlorophenyl)oxiranyl]phenyl-(221358-52-7)

Safety Data

• Hazardous Substances Data: 221358-52-7(Hazardous Substances Data)

Upstream product

• 14531-55-6 3,5-dimethyl-4-nitro-1H-pyrazole 
• 587-04-2 m-Chlorobenzaldehyde 
• 98-86-2 acetophenone 
• 22966-13-8 3-(3-chlorophenyl)-1-phenylprop-2-en-1-one 

Relevant articles and documents

Asymmetric epoxidation of α,β-unsaturated ketones catalyzed by rare-earth metal amides RE[N(SiMe3)2]3with chiral TADDOL ligands

The catalytic asymmetric epoxidation of α,β-unsaturated ketones by tert-butylhydroperoxide (TBHP) has been well established using rare-earth metal amides RE[N(SiMe3)2]3 (RE = La(1), Nd(2), Sm(3), Y(4), Yb(5)) with chiral TADDOL ligands. It was found that

Lanthanide complexes combined with chiral salen ligands: Application in the enantioselective epoxidation reaction of α,β-unsaturated ketones

Readily available lanthanide amides Ln[N(SiMe3)2]3 (Ln = Nd (1), Sm (2), Eu (3), Yb (4), La (5)), combined with chiral salen ligands H2La ((S,S)-N,N′-di-(3,5-disubstituted-salicylidene)-1,2-cyclohexan

Kinetic resolution of 2,3-epoxy 3-aryl ketones via catalytic asymmetric ring-opening with pyrazole derivatives

A highly efficient catalytic kinetic resolution of 2,3-epoxy 3-aryl ketones via asymmetric ring-opening with pyrazole derivatives has been achieved by using a chiral N,N′-dioxide-Sc(III) complex as the catalyst. A wide variety of substrates were readily scoped, and the selectivity factors obtained were excellent (up to >300).