221445-39-2Relevant academic research and scientific papers
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series
Song, Yuntao,Connor, David T.,Doubleday, Robert,Sorenson, Roderick J.,Sercel, Anthony D.,Unangst, Paul C.,Roth, Bruce D.,Gilbertsen, Richard B.,Chan, Kam,Schrier, Denis J.,Guglietta, Antonio,Bornemeier, Dirk A.,Dyer, Richard D.
, p. 1151 - 1160 (2007/10/03)
Selective cyclooxygenase-2 (COX-2) inhibitors have been shown to be potent antiinflammatory agents with fewer side effects than currently marketed nonsteroidal antiinflammatory drugs (NSAIDs). Initial mass screening and subsequent structure-activity relat
