221467-90-9Relevant academic research and scientific papers
Catalytic Asymmetric Dihydroxylation of Aliphatic Olefins with Reusable Resin-Osmium Tetroxide
Choudary, Boyapati M.,Jyothi, Karangula,Madhi, Sateesh,Kantam, M. Lakshmi
, p. 1190 - 1192 (2007/10/03)
Asymmetric dihydroxylation of aliphatic olefins to chiral diols with good yields and ees by a heterogeneous Resin-OsO4 catalyst using ferricyanide as cooxidant is disclosed for the first time. The catalyst was recovered quantitatively by simple filtration and reused for several times without significant loss of activity.
Eine neue Ligandenklasse fuer die asymmetrische Dihydroxylierung von Olefinen
Becker, Heinrich,Sharpless, K. Barry
, p. 447 - 449 (2007/10/03)
Keywords: Asymmetrische Dihydroxylierungen; Chirale Liganden; Chinchonaalkaloide; Katalyse; Osmiumverbindungen
Asymmetric Dihydroxylation of Primary Allylic Halides and a Concise Synthesis of (-)-Diepoxybutane
Vanhessche, Koen P. M.,Wang, Zhi-Min,Sharpless, K. Barry
, p. 3469 - 3472 (2007/10/02)
The asymmetric dihydroxylation (AD) of primary allylic halides is described.Enantiomeric excesses range from 40 to 98percent.Subsequent base treatment gives epoxy alcohols in high yields.This strategy is further illustrated by the synthesis of (-)-diepoxybutane, an important C4-chiral building block.
