22155-90-4Relevant academic research and scientific papers
Synthesis and characterization of chiral 1,2-diamines from 5-oxo-pyrrolidine-(S)-2-carboxylic acid
Koehn, Uwe,Schramm, Andrea,Kloss, Florian,Goerls, Helmar,Arnold, Evelyn,Anders, Ernst
, p. 1735 - 1741 (2007)
Unsymmetrical chiral secondary vicinal diamines were synthesized by applying a modified three-step reaction. The key step in this sequence is a primary amine mediated ring opening reaction of a diastereomeric oxazolidinone derivative. A possible mechanism
Chiral diamides as efficient catalytic precursors for the borane-mediated asymmetric reduction of prochiral ketones
Basavaiah, Deevi,Venkateswara Rao, Kalapala,Sekhara Reddy, Bhavanam
, p. 968 - 974 (2007)
Chiral diamides [(2S)-5-oxo-2-(arylamino)carbonylpyrrolidines] derived from the abundantly available (S)-glutamic/(S)-pyroglutamic acids were successfully utilized as effective chiral catalytic precursors in the borane-mediated asymmetric reduction of prochiral ketones in refluxing toluene, to provide the corresponding secondary alcohols with up to 91% enantiomeric purities.
