22160-86-7Relevant articles and documents
Synthesis of (+)-Taxodione
Haslinger, Ernst,Michl, Guenter
, p. 677 - 686 (2007/10/02)
A stereoselective synthesis of (+)-taxodione (1) starting from (-)-abietic acid (2) via the ironcarbonyl complex 4 is described.Conversion of the carboxyl function of 4 into a methyl group via 5 and 6 proceeds in excellent overall yield.The next steps are the introduction of oxygen functions in the positions 12 and 6.Oxidation with BSA yields the quinonemethide 1.The 1H- and 13C-NMR resonances of all compounds have been assigned.