221616-78-0Relevant articles and documents
Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2',3'- unsaturated L-nucleosides
Lee, Kyeong,Choi, Yongseok,Gullen, Elizabeth,Schlueter-Wirtz, Susan,Schinazi, Raymond F.,Cheng, Yung-Chi,Chu, Chung K.
, p. 1320 - 1328 (1999)
The synthesis of L-nucleoside analogues containing 2'-vinylic fluoride was accomplished by direct condensation method, and their anti-HIV and anti- HBV activities were evaluated in vitro. The key intermediate 8, the sugar moiety of our target compounds, w