221700-27-2Relevant academic research and scientific papers
Synthesis of a chiral dendrimer based on polyfunctional amino acids
Ritzen, Andreas,Frejd, Torbjoern
, p. 207 - 208 (1999)
A chiral, nonracemic dendrimer of generation two based on aromatic bis- and tris-amino acids has been synthesised.
Synthesis of an optically active C3-symmetric cage-like trisamide
Ionescu,Frejd
, p. 1088 - 1089 (2001)
The synthesis of the optically active C3-symmetric cage-like trisamide 2 was easily accomplished by the reaction of lb with Kemp's triacid; structure elucidation revealed the presence of an array of H-bonds closing the structure as a capsule.
Chiral, polyionic dendrimers with complementary charges - Synthesis and chiroptical properties
Ritzen, Andreas,Frejd, Torbjoern
, p. 3771 - 3782 (2007/10/03)
Chiral dendrimers up to the second generation have been prepared from enantiopure aromatic bis- and tris(amino acids) by peptide coupling techniques. The dendrimers could be deprotected to yield water-soluble polyamine and/or polycarboxylic acid macromolecules. Two complementary types, with respect to the charges carried in water at pH = 7, were synthesised. A chiroptical study of the protected dendrimers, which were soluble in THF and CHCl3, was conducted. The results of that study indicate that the solution shapes of these dendrimers are rather decongested, with little steric interaction between different parts of the dendritic structure.
