22179-31-3

Basic information

• Product Name: 4-(4-CHLORO-3-NITRO-BENZENESULFONYL)-MORPHOLINE
• Synonyms: 4-[(4-Chloro-3-nitrophenyl)sulfonyl]morpholine
• CAS NO: 22179-31-3
• Molecular Formula: C₁₀H₁₁ClN₂O₅S
• Molecular Weight: 306.72
• Mol File: 22179-31-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 471.2°Cat760mmHg
• Flash Point: 238.8°C
• Appearance: /
• Density: 1.536g/cm³
• Vapor Pressure: 4.74E-09mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 4-(4-CHLORO-3-NITRO-BENZENESULFONYL)-MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-CHLORO-3-NITRO-BENZENESULFONYL)-MORPHOLINE(22179-31-3)
• EPA Substance Registry System: 4-(4-CHLORO-3-NITRO-BENZENESULFONYL)-MORPHOLINE(22179-31-3)

Safety Data

• Hazardous Substances Data: 22179-31-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11ClN2O5S/c11-9-2-1-8(7-10(9)13(14)15)19(16,17)12-3-5-18-6-4-12/h1-2,7H,3-6H2

Upstream product

• 110-91-8 morpholine 
• 97-08-5 3-nitro-4-chlorosulfonyl chloride 

Downstream Products

• 17340-19-1 bis-[2-amino-4-(morpholine-4-sulfonyl)-phenyl]-disulfide 
• 174482-63-4 4-[(4-dimethylamino-3-valeramidobenzene)sulfonyl]morpholine 
• 174482-62-3 4-[(3-amino-4-dimethylaminobenzene)sulfonyl]morpholine 
• 56807-16-0 4-[(4-methoxy-3-nitrophenyl)sulfonyl]morpholine 
• 56807-17-1 2-methoxy-5-(morpholin-4-ylsulfonyl)aniline 
• 174482-61-2 4-[(4-dimethylamino-3-nitrobenzene)sulfonyl]morpholine 
• 862298-43-9 2,2-dimethyl-5-[4-(morpholin-4-ylsulfonyl)-2-nitrophenoxy]-4H-1,3-benzodioxin-4-one 
• 99170-49-7 4-(3-amino-4-mercapto-benzenesulfonyl)-morpholine 
• 99187-74-3 4-(3-amino-4-chloro-benzenesulfonyl)-morpholine 

Relevant articles and documents

MODIFIED BET-PROTEIN-INHIBITING DIHYDROQUINOXALINONES AND DIHYDROPYRIDOPYRAZINONES

The invention relates to BET-protein-inhibiting, in particular BRD4-inhibiting, dihydroquinoxalinones and dihydropyridopyrazinones of general formula (I), in which A, X, R1, R2, R3, R4, R5, R6, and n have the meanings indicated in the description, intermediate products for producing the compounds according to the invention, pharmaceutical agents containing the compounds according to the invention, and the prophylactic and therapeutic use of said pharmaceutical agents in the case of hyperproliferative diseases, in particular in the case of tumor diseases. The invention further relates to the use of BET protein inhibitors in the case of viral infections, neurodegenerative diseases, inflammatory diseases, and atherosclerotic diseases and in male fertility control.